Entity Details

Name GRK2_Ser375
ID P30411
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GRK6BDKRB2Ser375GTLRTSIsVERQIHKphosphorylation
down-regulates activity		11517230SIGNOR-251206
GRK4BDKRB2Ser375GTLRTSIsVERQIHKphosphorylation
down-regulates activity		11517230SIGNOR-249674
GRK2BDKRB2Ser375GTLRTSIsVERQIHKphosphorylation
down-regulates activity		11517230SIGNOR-251446
GRK5BDKRB2Ser375GTLRTSIsVERQIHKphosphorylation
down-regulates activity		11517230SIGNOR-251209
GRK3BDKRB2Ser375GTLRTSIsVERQIHKphosphorylation
down-regulates activity		11517230SIGNOR-251462
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GRK6phosphorylation
up-regulates
→
BDKRB2
PSer375		phosphorylation
down-regulates
⊣		BDKRB211517230SIGNOR-251206
GRK4phosphorylation
up-regulates
→
BDKRB2
PSer375		phosphorylation
down-regulates
⊣		BDKRB211517230SIGNOR-249674
GRK2phosphorylation
up-regulates
→
BDKRB2
PSer375		phosphorylation
down-regulates
⊣		BDKRB211517230SIGNOR-251446
GRK5phosphorylation
up-regulates
→
BDKRB2
PSer375		phosphorylation
down-regulates
⊣		BDKRB211517230SIGNOR-251209
GRK3phosphorylation
up-regulates
→
BDKRB2
PSer375		phosphorylation
down-regulates
⊣		BDKRB211517230SIGNOR-251462
Regulator Mechanism/Effect Target SIGNOR-ID
GRK6phosphorylation
→
down-regulates activity 		BDKRB2SIGNOR-251206
GRK4phosphorylation
→
down-regulates activity 		BDKRB2SIGNOR-249674
GRK2phosphorylation
→
down-regulates activity 		BDKRB2SIGNOR-251446
GRK5phosphorylation
→
down-regulates activity 		BDKRB2SIGNOR-251209
GRK3phosphorylation
→
down-regulates activity 		BDKRB2SIGNOR-251462