| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | SDHA | Tyr215 | SLRYDTSyFVEYFAL | phosphorylation up-regulates activity | 22823520 | SIGNOR-276420 |
| FGR | SDHA | Tyr543 | CGKISKLyGDLKHLK | phosphorylation unknown | 17997986 | SIGNOR-262872 |
| FGR | SDHA | Tyr604 | YKVRIDEyDYSKPIQ | phosphorylation unknown | 17997986 | SIGNOR-262873 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | SDHA PTyr215 | phosphorylation up-regulates → | SDHA | 22823520 | SIGNOR-276420 |
| FGR | phosphorylation up-regulates → | SDHA PTyr543 | phosphorylation down-regulates ⊣ | SDHA | 17997986 | SIGNOR-262872 |
| FGR | phosphorylation up-regulates → | SDHA PTyr604 | phosphorylation down-regulates ⊣ | SDHA | 17997986 | SIGNOR-262873 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates activity | SDHA | SIGNOR-276420 |
| FGR | phosphorylation → unknown | SDHA | SIGNOR-262872 |
| FGR | phosphorylation → unknown | SDHA | SIGNOR-262873 |
