Entity Details

Name MAPK4
ID P31152
Role kinase
Enzymatic Domains
Protein kinase 20-312
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK4AKT1Thr308KDGATMKtFCGTPEYphosphorylation
up-regulates activity		30688659SIGNOR-275450
MAPK4DUSP2–phosphorylation
up-regulates activity		28252035SIGNOR-278959
MAPK4MAPKAPK5Thr182IDQGDLMtPQFTPYYphosphorylation
up-regulates activity		20734105SIGNOR-279072
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK4phosphorylation
up-regulates
→
AKT1
PThr308		phosphorylation
up-regulates
→		AKT130688659SIGNOR-275450
MAPK4phosphorylation
up-regulates
→
MAPKAPK5
PThr182		phosphorylation
up-regulates
→		MAPKAPK520734105SIGNOR-279072
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK4phosphorylation
→
up-regulates activity 		AKT1SIGNOR-275450
MAPK4phosphorylation
→
up-regulates activity 		DUSP2SIGNOR-278959
MAPK4phosphorylation
→
up-regulates activity 		MAPKAPK5SIGNOR-279072