| Name | MAPK4 |
| ID | P31152 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 20-312 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DUSP2 | MAPK4 | – | dephosphorylation down-regulates activity | 28252035 | SIGNOR-277068 | |
| MAPKAPK5 | MAPK4 | Ser186 | YSHKGYLsEGLVTKW | phosphorylation up-regulates | 1319925 | SIGNOR-17069 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPKAPK5 | phosphorylation up-regulates → | MAPK4 PSer186 | phosphorylation up-regulates → | MAPK4 | 1319925 | SIGNOR-17069 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DUSP2 | dephosphorylation → down-regulates activity | MAPK4 | SIGNOR-277068 |
| MAPKAPK5 | phosphorylation → up-regulates | MAPK4 | SIGNOR-17069 |