Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAPKAPK5	MAPK4	Ser186 View in OncoXplorer	YSHKGYLsEGLVTKW	phosphorylation up-regulates	1319925	SIGNOR-17069

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPKAPK5	phosphorylation up-regulates →	MAPK4 PSer186	phosphorylation up-regulates →	MAPK4	1319925	SIGNOR-17069

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAPKAPK5	phosphorylation → up-regulates	MAPK4	SIGNOR-17069