Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CDK1	RRM2	Thr33 View in OncoXplorer	SLVDKENtPPALSGT	phosphorylation down-regulates	22632967	SIGNOR-197630
CDK1	RRM2	Ser20 View in OncoXplorer	DPQQLQLsPLKGLSL	phosphorylation unknown	9990288	SIGNOR-64312

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CDK1	phosphorylation up-regulates →	RRM2 PThr33	phosphorylation down-regulates ⊣	RRM2	22632967	SIGNOR-197630
CDK1	phosphorylation up-regulates →	RRM2 PSer20	phosphorylation down-regulates ⊣	RRM2	9990288	SIGNOR-64312

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CDK1	phosphorylation down-regulates	RRM2	SIGNOR-197630
CDK1	phosphorylation → unknown	RRM2	SIGNOR-64312