Entity Details

Name PRKCZ_Thr309
ID P31751
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PDPK1AKT2Thr309SDGATMKtFCGTPEYphosphorylation
up-regulates activity		9512493SIGNOR-236785
PRKCZAKT2Thr309SDGATMKtFCGTPEYphosphorylation
up-regulates activity		9512493SIGNOR-248997
PPP2CAAKT2Thr309SDGATMKtFCGTPEYdephosphorylation
down-regulates activity		15367694SIGNOR-248633
PDPK1AKT2Thr309SDGATMKtFCGTPEYphosphorylation
up-regulates activity		15743829SIGNOR-134485
PPP2CAAKT2Thr309SDGATMKtFCGTPEYdephosphorylation
down-regulates activity		18160256SIGNOR-248630
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PDPK1phosphorylation
up-regulates
→
AKT2
PThr309		phosphorylation
up-regulates
→		AKT29512493SIGNOR-236785
PRKCZphosphorylation
up-regulates
→
AKT2
PThr309		phosphorylation
up-regulates
→		AKT29512493SIGNOR-248997
PPP2CAdephosphorylation
down-regulates
⊣
AKT2
PThr309		dephosphorylation
up-regulates
→		AKT215367694SIGNOR-248633
PDPK1phosphorylation
up-regulates
→
AKT2
PThr309		phosphorylation
up-regulates
→		AKT215743829SIGNOR-134485
PPP2CAdephosphorylation
down-regulates
⊣
AKT2
PThr309		dephosphorylation
up-regulates
→		AKT218160256SIGNOR-248630
Regulator Mechanism/Effect Target SIGNOR-ID
PDPK1phosphorylation
→
up-regulates activity 		AKT2SIGNOR-236785
PRKCZphosphorylation
→
up-regulates activity 		AKT2SIGNOR-248997
PPP2CAdephosphorylation
→
down-regulates activity 		AKT2SIGNOR-248633
PDPK1phosphorylation
→
up-regulates activity 		AKT2SIGNOR-134485
PPP2CAdephosphorylation
→
down-regulates activity 		AKT2SIGNOR-248630