Entity Details

Name FCGR2C
ID P31995
Role substrate
Enzymatic Domains
Ig-like C2-type 1 48-127
Ig-like C2-type 2 131-213
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SYKFCGR2CTyr310TDDDKNIyLTLPPNDphosphorylation
up-regulates activity		8756631SIGNOR-262675
BLKFCGR2CTyr310TDDDKNIyLTLPPNDphosphorylation
up-regulates activity		8756631SIGNOR-262673
FYNFCGR2CTyr294YETADGGyMTLNPRAphosphorylation
up-regulates activity		8756631SIGNOR-262677
BLKFCGR2CTyr294YETADGGyMTLNPRAphosphorylation
up-regulates activity		8756631SIGNOR-262672
SYKFCGR2CTyr287PEETNNDyETADGGYphosphorylation
up-regulates activity		8756631SIGNOR-262674
LYNFCGR2CTyr310TDDDKNIyLTLPPNDphosphorylation
up-regulates activity		8756631SIGNOR-262676
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SYKphosphorylation
up-regulates
→
FCGR2C
PTyr310		phosphorylation
up-regulates
→		FCGR2C8756631SIGNOR-262675
BLKphosphorylation
up-regulates
→
FCGR2C
PTyr310		phosphorylation
up-regulates
→		FCGR2C8756631SIGNOR-262673
FYNphosphorylation
up-regulates
→
FCGR2C
PTyr294		phosphorylation
up-regulates
→		FCGR2C8756631SIGNOR-262677
BLKphosphorylation
up-regulates
→
FCGR2C
PTyr294		phosphorylation
up-regulates
→		FCGR2C8756631SIGNOR-262672
SYKphosphorylation
up-regulates
→
FCGR2C
PTyr287		phosphorylation
up-regulates
→		FCGR2C8756631SIGNOR-262674
LYNphosphorylation
up-regulates
→
FCGR2C
PTyr310		phosphorylation
up-regulates
→		FCGR2C8756631SIGNOR-262676
Regulator Mechanism/Effect Target SIGNOR-ID
SYKphosphorylation
→
up-regulates activity 		FCGR2CSIGNOR-262675
BLKphosphorylation
→
up-regulates activity 		FCGR2CSIGNOR-262673
FYNphosphorylation
→
up-regulates activity 		FCGR2CSIGNOR-262677
BLKphosphorylation
→
up-regulates activity 		FCGR2CSIGNOR-262672
SYKphosphorylation
→
up-regulates activity 		FCGR2CSIGNOR-262674
LYNphosphorylation
→
up-regulates activity 		FCGR2CSIGNOR-262676