| Name | L1CAM |
| ID | P32004 |
| Role | substrate |
| Enzymatic Domains |
Ig-like C2-type 1 35-125
Ig-like C2-type 2 139-226
Ig-like C2-type 3 240-328
Ig-like C2-type 4 333-420
Ig-like C2-type 5 425-507
Ig-like C2-type 6 518-607
Fibronectin type-III 1 615-712 PROSITE-ProRule
Fibronectin type-III 2 717-810 PROSITE-ProRule
Fibronectin type-III 3 814-916 PROSITE-ProRule
Fibronectin type-III 4 920-1015 PROSITE-ProRule
Fibronectin type-III 5 1016-1115 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA2 | L1CAM | Ser1152 | RSKGGKYsVKDKEDT | phosphorylation up-regulates activity | 8663493 | SIGNOR-248949 |
| CSNK2A1 | L1CAM | Ser1181 | GEYRSLEsDNEEKAF | phosphorylation unknown | 8592152 | SIGNOR-250913 |
| RPS6K | L1CAM | Ser1152 | RSKGGKYsVKDKEDT | phosphorylation up-regulates activity | 8663493 | SIGNOR-252766 |
| PRKCA | L1CAM | Thr1172 | ARPMKDEtFGEYRSL | phosphorylation down-regulates activity | 20335502 | SIGNOR-276283 |
| RPS6KA1 | L1CAM | Ser1152 | RSKGGKYsVKDKEDT | phosphorylation up-regulates activity | 8663493 | SIGNOR-248948 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA2 | phosphorylation up-regulates → | L1CAM PSer1152 | phosphorylation up-regulates → | L1CAM | 8663493 | SIGNOR-248949 |
| CSNK2A1 | phosphorylation up-regulates → | L1CAM PSer1181 | phosphorylation down-regulates ⊣ | L1CAM | 8592152 | SIGNOR-250913 |
| RPS6K | phosphorylation up-regulates → | L1CAM PSer1152 | phosphorylation up-regulates → | L1CAM | 8663493 | SIGNOR-252766 |
| PRKCA | phosphorylation up-regulates → | L1CAM PThr1172 | phosphorylation down-regulates ⊣ | L1CAM | 20335502 | SIGNOR-276283 |
| RPS6KA1 | phosphorylation up-regulates → | L1CAM PSer1152 | phosphorylation up-regulates → | L1CAM | 8663493 | SIGNOR-248948 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6KA2 | phosphorylation → up-regulates activity | L1CAM | SIGNOR-248949 |
| CSNK2A1 | phosphorylation → unknown | L1CAM | SIGNOR-250913 |
| RPS6K | phosphorylation → up-regulates activity | L1CAM | SIGNOR-252766 |
| PRKCA | phosphorylation → down-regulates activity | L1CAM | SIGNOR-276283 |
| RPS6KA1 | phosphorylation → up-regulates activity | L1CAM | SIGNOR-248948 |