| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKG2 | CTH | Ser377 | SDTLIRLsVGLEDEE | phosphorylation down-regulates activity | 25900831 | SIGNOR-275800 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKG2 | phosphorylation up-regulates → | CTH PSer377 | phosphorylation down-regulates ⊣ | CTH | 25900831 | SIGNOR-275800 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKG2 | phosphorylation → down-regulates activity | CTH | SIGNOR-275800 |