| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| JAK3 | CTNNB1 | Tyr64 | VDTSQVLyEWEQGFS | phosphorylation up-regulates activity | 28821617 | SIGNOR-278179 |
| PTK6 | CTNNB1 | Tyr64 | VDTSQVLyEWEQGFS | phosphorylation down-regulates quantity | 20026641 | SIGNOR-278288 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| JAK3 | phosphorylation up-regulates → | CTNNB1 PTyr64 | phosphorylation up-regulates → | CTNNB1 | 28821617 | SIGNOR-278179 |
| PTK6 | phosphorylation up-regulates → | CTNNB1 PTyr64 | phosphorylation down-regulates ⊣ | CTNNB1 | 20026641 | SIGNOR-278288 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| JAK3 | phosphorylation → up-regulates activity | CTNNB1 | SIGNOR-278179 |
| PTK6 | phosphorylation → down-regulates quantity | CTNNB1 | SIGNOR-278288 |