| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTK6 | CTNNB1 | Tyr142 | AVVNLINyQDDAELA | phosphorylation down-regulates quantity | 20026641 | SIGNOR-278286 |
| PTK2 | CTNNB1 | Tyr142 | AVVNLINyQDDAELA | phosphorylation unknown | 22264731 | SIGNOR-261946 |
| NTRK1 | CTNNB1 | Tyr142 | AVVNLINyQDDAELA | phosphorylation up-regulates activity | 22558232 | SIGNOR-279240 |
| FYN | CTNNB1 | Tyr142 | AVVNLINyQDDAELA | phosphorylation down-regulates activity | 12640114 | SIGNOR-251162 |
| FER | CTNNB1 | Tyr142 | AVVNLINyQDDAELA | phosphorylation down-regulates activity | 12640114 | SIGNOR-251131 |
| EGFR | CTNNB1 | Tyr142 | AVVNLINyQDDAELA | phosphorylation up-regulates activity | 22558232 | SIGNOR-278309 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTK6 | phosphorylation up-regulates → | CTNNB1 PTyr142 | phosphorylation down-regulates ⊣ | CTNNB1 | 20026641 | SIGNOR-278286 |
| PTK2 | phosphorylation up-regulates → | CTNNB1 PTyr142 | phosphorylation down-regulates ⊣ | CTNNB1 | 22264731 | SIGNOR-261946 |
| NTRK1 | phosphorylation up-regulates → | CTNNB1 PTyr142 | phosphorylation up-regulates → | CTNNB1 | 22558232 | SIGNOR-279240 |
| FYN | phosphorylation up-regulates → | CTNNB1 PTyr142 | phosphorylation down-regulates ⊣ | CTNNB1 | 12640114 | SIGNOR-251162 |
| FER | phosphorylation up-regulates → | CTNNB1 PTyr142 | phosphorylation down-regulates ⊣ | CTNNB1 | 12640114 | SIGNOR-251131 |
| EGFR | phosphorylation up-regulates → | CTNNB1 PTyr142 | phosphorylation up-regulates → | CTNNB1 | 22558232 | SIGNOR-278309 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTK6 | phosphorylation → down-regulates quantity | CTNNB1 | SIGNOR-278286 |
| PTK2 | phosphorylation → unknown | CTNNB1 | SIGNOR-261946 |
| NTRK1 | phosphorylation → up-regulates activity | CTNNB1 | SIGNOR-279240 |
| FYN | phosphorylation → down-regulates activity | CTNNB1 | SIGNOR-251162 |
| FER | phosphorylation → down-regulates activity | CTNNB1 | SIGNOR-251131 |
| EGFR | phosphorylation → up-regulates activity | CTNNB1 | SIGNOR-278309 |
