| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTK6 | CTNNB1 | Tyr333 | NIMRTYTyEKLLWTT | phosphorylation down-regulates quantity | 20026641 | SIGNOR-278289 |
| SRC | CTNNB1 | Tyr333 | NIMRTYTyEKLLWTT | phosphorylation up-regulates | 22056988 | SIGNOR-177086 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTK6 | phosphorylation up-regulates → | CTNNB1 PTyr333 | phosphorylation down-regulates ⊣ | CTNNB1 | 20026641 | SIGNOR-278289 |
| SRC | phosphorylation up-regulates → | CTNNB1 PTyr333 | phosphorylation up-regulates → | CTNNB1 | 22056988 | SIGNOR-177086 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTK6 | phosphorylation → down-regulates quantity | CTNNB1 | SIGNOR-278289 |
| SRC | phosphorylation → up-regulates | CTNNB1 | SIGNOR-177086 |