Entity Details

Name BMI1
ID P35226
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
Membrane_blebbingBMI1Ser316ANRPRKSsVNGSSATphosphorylation
up-regulates activity		22505453SIGNOR-249584
AKT1BMI1Ser316ANRPRKSsVNGSSATphosphorylation
up-regulates activity		22505453SIGNOR-252559
AKT3BMI1Ser316ANRPRKSsVNGSSATphosphorylation
up-regulates activity		22505453SIGNOR-249583
CSNK2A1BMI1Ser110SADAANGsNEDRGEVphosphorylation
down-regulates quantity by destabilization		28270146SIGNOR-277345
AKTBMI1Ser316ANRPRKSsVNGSSATphosphorylation
up-regulates activity		22505453SIGNOR-249581
AKT2BMI1Ser316ANRPRKSsVNGSSATphosphorylation
up-regulates activity		22505453SIGNOR-249582
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
Membrane_blebbingphosphorylation
up-regulates
→
BMI1
PSer316		phosphorylation
up-regulates
→		BMI122505453SIGNOR-249584
AKT1phosphorylation
up-regulates
→
BMI1
PSer316		phosphorylation
up-regulates
→		BMI122505453SIGNOR-252559
AKT3phosphorylation
up-regulates
→
BMI1
PSer316		phosphorylation
up-regulates
→		BMI122505453SIGNOR-249583
CSNK2A1phosphorylation
up-regulates
→
BMI1
PSer110		phosphorylation
down-regulates
⊣		BMI128270146SIGNOR-277345
AKTphosphorylation
up-regulates
→
BMI1
PSer316		phosphorylation
up-regulates
→		BMI122505453SIGNOR-249581
AKT2phosphorylation
up-regulates
→
BMI1
PSer316		phosphorylation
up-regulates
→		BMI122505453SIGNOR-249582
Regulator Mechanism/Effect Target SIGNOR-ID
Membrane_blebbingphosphorylation
→
up-regulates activity 		BMI1SIGNOR-249584
AKT1phosphorylation
→
up-regulates activity 		BMI1SIGNOR-252559
AKT3phosphorylation
→
up-regulates activity 		BMI1SIGNOR-249583
CSNK2A1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		BMI1SIGNOR-277345
AKTphosphorylation
→
up-regulates activity 		BMI1SIGNOR-249581
AKT2phosphorylation
→
up-regulates activity 		BMI1SIGNOR-249582