| Name | DDIT3 |
| ID | P35638 |
| Role | substrate |
| Enzymatic Domains |
bZIP 99-162 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | DDIT3 | Ser30 | EDLQEVLsSDENGGT | phosphorylation down-regulates activity | 12876286 | SIGNOR-250852 |
| PRKAA1 | DDIT3 | Ser30 | EDLQEVLsSDENGGT | phosphorylation down-regulates quantity | 27650555 | SIGNOR-278381 |
| MAPK14 | DDIT3 | Ser79 | EVTSTSQsPHSPDSS | phosphorylation up-regulates activity | 8650547 | SIGNOR-42200 |
| CSNK2A1 | DDIT3 | Ser14 | PFSFGTLsSWELEAW | phosphorylation down-regulates activity | 12876286 | SIGNOR-250850 |
| MAPK14 | DDIT3 | Ser82 | STSQSPHsPDSSQSS | phosphorylation up-regulates activity | 8650547 | SIGNOR-250096 |
| PRKAA1 | DDIT3 | Ser30 | EDLQEVLsSDENGGT | phosphorylation down-regulates activity | 27650555 | SIGNOR-259864 |
| CSNK2A1 | DDIT3 | Ser31 | DLQEVLSsDENGGTY | phosphorylation down-regulates activity | 12876286 | SIGNOR-250853 |
| CSNK2A1 | DDIT3 | Ser15 | FSFGTLSsWELEAWY | phosphorylation down-regulates activity | 12876286 | SIGNOR-250851 |
| p38 | DDIT3 | – | phosphorylation up-regulates activity | 8650547 | SIGNOR-260724 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | phosphorylation up-regulates → | DDIT3 PSer30 | phosphorylation down-regulates ⊣ | DDIT3 | 12876286 | SIGNOR-250852 |
| PRKAA1 | phosphorylation up-regulates → | DDIT3 PSer30 | phosphorylation down-regulates ⊣ | DDIT3 | 27650555 | SIGNOR-278381 |
| MAPK14 | phosphorylation up-regulates → | DDIT3 PSer79 | phosphorylation up-regulates → | DDIT3 | 8650547 | SIGNOR-42200 |
| CSNK2A1 | phosphorylation up-regulates → | DDIT3 PSer14 | phosphorylation down-regulates ⊣ | DDIT3 | 12876286 | SIGNOR-250850 |
| MAPK14 | phosphorylation up-regulates → | DDIT3 PSer82 | phosphorylation up-regulates → | DDIT3 | 8650547 | SIGNOR-250096 |
| PRKAA1 | phosphorylation up-regulates → | DDIT3 PSer30 | phosphorylation down-regulates ⊣ | DDIT3 | 27650555 | SIGNOR-259864 |
| CSNK2A1 | phosphorylation up-regulates → | DDIT3 PSer31 | phosphorylation down-regulates ⊣ | DDIT3 | 12876286 | SIGNOR-250853 |
| CSNK2A1 | phosphorylation up-regulates → | DDIT3 PSer15 | phosphorylation down-regulates ⊣ | DDIT3 | 12876286 | SIGNOR-250851 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A1 | phosphorylation → down-regulates activity | DDIT3 | SIGNOR-250852 |
| PRKAA1 | phosphorylation → down-regulates quantity | DDIT3 | SIGNOR-278381 |
| MAPK14 | phosphorylation → up-regulates activity | DDIT3 | SIGNOR-42200 |
| CSNK2A1 | phosphorylation → down-regulates activity | DDIT3 | SIGNOR-250850 |
| MAPK14 | phosphorylation → up-regulates activity | DDIT3 | SIGNOR-250096 |
| PRKAA1 | phosphorylation → down-regulates activity | DDIT3 | SIGNOR-259864 |
| CSNK2A1 | phosphorylation → down-regulates activity | DDIT3 | SIGNOR-250853 |
| CSNK2A1 | phosphorylation → down-regulates activity | DDIT3 | SIGNOR-250851 |
| p38 | phosphorylation → up-regulates activity | DDIT3 | SIGNOR-260724 |