Entity Details

Name KDR
ID P35968
Role kinase
Enzymatic Domains
Ig-like C2-type 1 46-110
Ig-like C2-type 2 141-207
Ig-like C2-type 3 224-320
Ig-like C2-type 4 328-414
Ig-like C2-type 5 421-548
Ig-like C2-type 6 551-660
Ig-like C2-type 7 667-753
Protein kinase 834-1162
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
KDRKDRTyr996EEAPEDLyKDFLTLEphosphorylation
up-regulates		10102632SIGNOR-66040
KDRKDRTyr1054FGLARDIyKDPDYVRphosphorylation
up-regulates		17658244SIGNOR-157081
KDRKDRTyr1059DIYKDPDyVRKGDARphosphorylation
up-regulates		17658244SIGNOR-157085
KDRKDRTyr1175AQQDGKDyIVLPISEphosphorylation
up-regulates		17658244SIGNOR-157089
KDRKDRTyr1214VCDPKFHyDNTAGISphosphorylation
up-regulates		17658244SIGNOR-157093
KDRKDRTyr951RFRQGKDyVGAIPVDphosphorylation
up-regulates		17658244SIGNOR-157097
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
KDRphosphorylation
up-regulates
→
KDR
PTyr996		phosphorylation
up-regulates
→		KDR10102632SIGNOR-66040
KDRphosphorylation
up-regulates
→
KDR
PTyr1054		phosphorylation
up-regulates
→		KDR17658244SIGNOR-157081
KDRphosphorylation
up-regulates
→
KDR
PTyr1059		phosphorylation
up-regulates
→		KDR17658244SIGNOR-157085
KDRphosphorylation
up-regulates
→
KDR
PTyr1175		phosphorylation
up-regulates
→		KDR17658244SIGNOR-157089
KDRphosphorylation
up-regulates
→
KDR
PTyr1214		phosphorylation
up-regulates
→		KDR17658244SIGNOR-157093
KDRphosphorylation
up-regulates
→
KDR
PTyr951		phosphorylation
up-regulates
→		KDR17658244SIGNOR-157097
Regulator Mechanism/Effect Target SIGNOR-ID
KDRphosphorylation
→
up-regulates 		KDRSIGNOR-66040
KDRphosphorylation
→
up-regulates 		KDRSIGNOR-157081
KDRphosphorylation
→
up-regulates 		KDRSIGNOR-157085
KDRphosphorylation
→
up-regulates 		KDRSIGNOR-157089
KDRphosphorylation
→
up-regulates 		KDRSIGNOR-157093
KDRphosphorylation
→
up-regulates 		KDRSIGNOR-157097