| Name | BMPR1A |
| ID | P36894 |
| Role | kinase |
| Enzymatic Domains |
GS 204-233 PROSITE-ProRule
Protein kinase 234-525 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BMPR1A | FAM83G | Ser610 | GPGPRRPsVASSVSE | phosphorylation up-regulates activity | 24554596 | SIGNOR-264765 |
| BMPR1A | FAM83G | Ser614 | RRPSVASsVSEEYFE | phosphorylation up-regulates activity | 24554596 | SIGNOR-264766 |
| BMPR1A | FAM83G | Ser616 | PSVASSVsEEYFEVR | phosphorylation up-regulates activity | 24554596 | SIGNOR-264767 |
| BMPR1A | SMAD9 | – | phosphorylation up-regulates activity | 19620713 | SIGNOR-255772 | |
| BMPR1A | SMAD1 | – | phosphorylation up-regulates | 19620713 | SIGNOR-187181 | |
| BMPR1A | SMAD1 | Ser463 | SPHNPISsVS | phosphorylation up-regulates | 9136927 | SIGNOR-210084 |
| BMPR1A | SMAD1 | Ser465 | HNPISSVs | phosphorylation up-regulates | 9136927 | SIGNOR-249649 |
| BMPR1A | SMAD1 | – | phosphorylation up-regulates activity | 19620713 | SIGNOR-255263 | |
| BMPR1A | SMAD5 | – | phosphorylation up-regulates | 19620713 | SIGNOR-187184 | |
| BMPR1A | SMAD5 | – | phosphorylation up-regulates activity | 19620713 | SIGNOR-255261 | |
| BMPR1A | SMAD5/SMAD4 | – | phosphorylation up-regulates activity | 19620713 | SIGNOR-255788 | |
| BMPR1A | SMAD5/SMAD4 | – | phosphorylation up-regulates activity | 9442019 | SIGNOR-255779 | |
| BMPR1A | SMAD8/SMAD4 | – | phosphorylation up-regulates activity | 19620713 | SIGNOR-255786 | |
| BMPR1A | SMAD1/4 | – | phosphorylation up-regulates activity | 8893010 | SIGNOR-255778 | |
| BMPR1A | SMAD1/5/8 | – | phosphorylation up-regulates activity | 19620713 | SIGNOR-255831 | |
| BMPR1A | SMAD1/5/8 | – | phosphorylation up-regulates activity | 9442019 | SIGNOR-255830 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BMPR1A | phosphorylation up-regulates → | FAM83G PSer610 | phosphorylation up-regulates → | FAM83G | 24554596 | SIGNOR-264765 |
| BMPR1A | phosphorylation up-regulates → | FAM83G PSer614 | phosphorylation up-regulates → | FAM83G | 24554596 | SIGNOR-264766 |
| BMPR1A | phosphorylation up-regulates → | FAM83G PSer616 | phosphorylation up-regulates → | FAM83G | 24554596 | SIGNOR-264767 |
| BMPR1A | phosphorylation up-regulates → | SMAD1 PSer463 | phosphorylation up-regulates → | SMAD1 | 9136927 | SIGNOR-210084 |
| BMPR1A | phosphorylation up-regulates → | SMAD1 PSer465 | phosphorylation up-regulates → | SMAD1 | 9136927 | SIGNOR-249649 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| BMPR1A | phosphorylation → up-regulates activity | FAM83G | SIGNOR-264765 |
| BMPR1A | phosphorylation → up-regulates activity | FAM83G | SIGNOR-264766 |
| BMPR1A | phosphorylation → up-regulates activity | FAM83G | SIGNOR-264767 |
| BMPR1A | phosphorylation → up-regulates activity | SMAD9 | SIGNOR-255772 |
| BMPR1A | phosphorylation → up-regulates | SMAD1 | SIGNOR-187181 |
| BMPR1A | phosphorylation → up-regulates | SMAD1 | SIGNOR-210084 |
| BMPR1A | phosphorylation → up-regulates | SMAD1 | SIGNOR-249649 |
| BMPR1A | phosphorylation → up-regulates activity | SMAD1 | SIGNOR-255263 |
| BMPR1A | phosphorylation → up-regulates | SMAD5 | SIGNOR-187184 |
| BMPR1A | phosphorylation → up-regulates activity | SMAD5 | SIGNOR-255261 |
| BMPR1A | phosphorylation → up-regulates activity | SMAD5/SMAD4 | SIGNOR-255788 |
| BMPR1A | phosphorylation → up-regulates activity | SMAD5/SMAD4 | SIGNOR-255779 |
| BMPR1A | phosphorylation → up-regulates activity | SMAD8/SMAD4 | SIGNOR-255786 |
| BMPR1A | phosphorylation → up-regulates activity | SMAD1/4 | SIGNOR-255778 |
| BMPR1A | phosphorylation → up-regulates activity | SMAD1/5/8 | SIGNOR-255831 |
| BMPR1A | phosphorylation → up-regulates activity | SMAD1/5/8 | SIGNOR-255830 |