| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TGFBR2 | TGFBR1 | Thr176 | PFISEGTtLKDLIYD | phosphorylation up-regulates activity | 8576253 | SIGNOR-246732 |
| TGFBR2 | TGFBR1 | Thr176 | PFISEGTtLKDLIYD | phosphorylation up-regulates activity | 8576253 | SIGNOR-255961 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TGFBR2 | phosphorylation up-regulates → | TGFBR1 PThr176 | phosphorylation up-regulates → | TGFBR1 | 8576253 | SIGNOR-246732 |
| TGFBR2 | phosphorylation up-regulates → | TGFBR1 PThr176 | phosphorylation up-regulates → | TGFBR1 | 8576253 | SIGNOR-255961 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| TGFBR2 | phosphorylation → up-regulates activity | TGFBR1 | SIGNOR-246732 |
| TGFBR2 | phosphorylation → up-regulates activity | TGFBR1 | SIGNOR-255961 |