| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TGFBR2 | TGFBR1 | Thr200 | LPLLVQRtIARTIVL | phosphorylation up-regulates activity | 8576253 | SIGNOR-255962 |
| TGFBR2 | TGFBR1 | Thr200 | LPLLVQRtIARTIVL | phosphorylation up-regulates activity | 7774578 | SIGNOR-32744 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TGFBR2 | phosphorylation up-regulates → | TGFBR1 PThr200 | phosphorylation up-regulates → | TGFBR1 | 8576253 | SIGNOR-255962 |
| TGFBR2 | phosphorylation up-regulates → | TGFBR1 PThr200 | phosphorylation up-regulates → | TGFBR1 | 7774578 | SIGNOR-32744 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| TGFBR2 | phosphorylation → up-regulates activity | TGFBR1 | SIGNOR-255962 |
| TGFBR2 | phosphorylation → up-regulates activity | TGFBR1 | SIGNOR-32744 |