Entity Details

Name EGFR_Tyr102
ID P37231
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ABL1PPARGTyr102YDLKLQEyQSAIKVEphosphorylation
up-regulates quantity		25368164SIGNOR-262297
EGFRPPARGTyr102YDLKLQEyQSAIKVEphosphorylation
down-regulates quantity by destabilization		26718225SIGNOR-277190
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ABL1phosphorylation
up-regulates
→
PPARG
PTyr102		phosphorylation
up-regulates
→		PPARG25368164SIGNOR-262297
EGFRphosphorylation
up-regulates
→
PPARG
PTyr102		phosphorylation
down-regulates
⊣		PPARG26718225SIGNOR-277190
Regulator Mechanism/Effect Target SIGNOR-ID
ABL1phosphorylation
→
up-regulates quantity 		PPARGSIGNOR-262297
EGFRphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		PPARGSIGNOR-277190