Entity Details

Name MAPK1_Ser112
ID P37231
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1PPARGSer112AIKVEPAsPPYYSEKphosphorylation
down-regulates quantity by destabilization		11733495SIGNOR-112544
BCRPPARGSer112AIKVEPAsPPYYSEKphosphorylation
down-regulates activity		19023129SIGNOR-279441
MAPK3PPARGSer112AIKVEPAsPPYYSEKphosphorylation
down-regulates quantity by destabilization		11733495SIGNOR-179404
ERK1/2PPARGSer112AIKVEPAsPPYYSEKphosphorylation
up-regulates activity		11733495SIGNOR-232236
MAPK8PPARGSer112AIKVEPAsPPYYSEKphosphorylation
down-regulates activity		9030579SIGNOR-46518
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
PPARG
PSer112		phosphorylation
down-regulates
⊣		PPARG11733495SIGNOR-112544
BCRphosphorylation
up-regulates
→
PPARG
PSer112		phosphorylation
down-regulates
⊣		PPARG19023129SIGNOR-279441
MAPK3phosphorylation
up-regulates
→
PPARG
PSer112		phosphorylation
down-regulates
⊣		PPARG11733495SIGNOR-179404
ERK1/2phosphorylation
up-regulates
→
PPARG
PSer112		phosphorylation
up-regulates
→		PPARG11733495SIGNOR-232236
MAPK8phosphorylation
up-regulates
→
PPARG
PSer112		phosphorylation
down-regulates
⊣		PPARG9030579SIGNOR-46518
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		PPARGSIGNOR-112544
BCRphosphorylation
→
down-regulates activity 		PPARGSIGNOR-279441
MAPK3phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		PPARGSIGNOR-179404
ERK1/2phosphorylation
→
up-regulates activity 		PPARGSIGNOR-232236
MAPK8phosphorylation
→
down-regulates activity 		PPARGSIGNOR-46518