Entity Details

Name TAGLN2
ID P37802
Role substrate
Enzymatic Domains
Calponin-homology (CH) 24-136
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK14TAGLN2Ser163
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KENPRNFsDNQLQEGphosphorylation
down-regulates activity		21577206SIGNOR-265105
MAPK1TAGLN2Ser145
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ARDDGLFsGDPNWFPphosphorylation
up-regulates quantity by stabilization		30041673SIGNOR-265221
CDK14TAGLN2Ser83
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PVKKIQAsTMAFKQMphosphorylation
down-regulates activity		21577206SIGNOR-265103
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK14phosphorylation
up-regulates
→
TAGLN2
PSer163		phosphorylation
down-regulates
⊣		TAGLN221577206SIGNOR-265105
MAPK1phosphorylation
up-regulates
→
TAGLN2
PSer145		phosphorylation
up-regulates
→		TAGLN230041673SIGNOR-265221
CDK14phosphorylation
up-regulates
→
TAGLN2
PSer83		phosphorylation
down-regulates
⊣		TAGLN221577206SIGNOR-265103
Regulator Mechanism/Effect Target SIGNOR-ID
CDK14phosphorylation
→
down-regulates activity 		TAGLN2SIGNOR-265105
MAPK1phosphorylation
→
up-regulates quantity by stabilization 		TAGLN2SIGNOR-265221
CDK14phosphorylation
→
down-regulates activity 		TAGLN2SIGNOR-265103