| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SYK | SNCA | Tyr125 | VDPDNEAyEMPSEEG | phosphorylation down-regulates | 11744621 | SIGNOR-113061 |
| PTK2B | SNCA | Tyr125 | VDPDNEAyEMPSEEG | phosphorylation unknown | 12096713 | SIGNOR-249151 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SYK | phosphorylation up-regulates → | SNCA PTyr125 | phosphorylation down-regulates ⊣ | SNCA | 11744621 | SIGNOR-113061 |
| PTK2B | phosphorylation up-regulates → | SNCA PTyr125 | phosphorylation down-regulates ⊣ | SNCA | 12096713 | SIGNOR-249151 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SYK | phosphorylation down-regulates | SNCA | SIGNOR-113061 |
| PTK2B | phosphorylation → unknown | SNCA | SIGNOR-249151 |
