Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PPP1CA	BRCA1	Ser1524 View in OncoXplorer	LQNRNYPsQEELIKV	dephosphorylation down-regulates activity	17603999	SIGNOR-248562
ATM	BRCA1	Ser1524 View in OncoXplorer	LQNRNYPsQEELIKV	phosphorylation up-regulates	10550055	SIGNOR-72068
ATM	BRCA1	Ser1524 View in OncoXplorer	LQNRNYPsQEELIKV	phosphorylation unknown	10550055	SIGNOR-72079

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PPP1CA	dephosphorylation down-regulates ⊣	BRCA1 PSer1524	dephosphorylation up-regulates →	BRCA1	17603999	SIGNOR-248562
ATM	phosphorylation up-regulates →	BRCA1 PSer1524	phosphorylation up-regulates →	BRCA1	10550055	SIGNOR-72068
ATM	phosphorylation up-regulates →	BRCA1 PSer1524	phosphorylation down-regulates ⊣	BRCA1	10550055	SIGNOR-72079

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PPP1CA	dephosphorylation → down-regulates activity	BRCA1	SIGNOR-248562
ATM	phosphorylation → up-regulates	BRCA1	SIGNOR-72068
ATM	phosphorylation → unknown	BRCA1	SIGNOR-72079