Entity Details

Name CD79B
ID P40259
Role substrate
Enzymatic Domains
Ig-like V-type 38-138
ITAM 185-213
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LYNCD79BTyr196GMEEDHTyEGLDIDQphosphorylation
up-regulates activity		9531288SIGNOR-251398
SH2B1CD79B–dephosphorylation
down-regulates activity		32323266SIGNOR-268458
FYNCD79BTyr196GMEEDHTyEGLDIDQphosphorylation
up-regulates activity		9531288SIGNOR-251154
FYNCD79BTyr207DIDQTATyEDIVTLRphosphorylation
up-regulates activity		9531288SIGNOR-251155
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LYNphosphorylation
up-regulates
→
CD79B
PTyr196		phosphorylation
up-regulates
→		CD79B9531288SIGNOR-251398
FYNphosphorylation
up-regulates
→
CD79B
PTyr196		phosphorylation
up-regulates
→		CD79B9531288SIGNOR-251154
FYNphosphorylation
up-regulates
→
CD79B
PTyr207		phosphorylation
up-regulates
→		CD79B9531288SIGNOR-251155
Regulator Mechanism/Effect Target SIGNOR-ID
LYNphosphorylation
→
up-regulates activity 		CD79BSIGNOR-251398
SH2B1dephosphorylation
→
down-regulates activity 		CD79BSIGNOR-268458
FYNphosphorylation
→
up-regulates activity 		CD79BSIGNOR-251154
FYNphosphorylation
→
up-regulates activity 		CD79BSIGNOR-251155