| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| NEK1 | VHL | Ser168 | RCLQVVRsLVKPENY | phosphorylation down-regulates quantity by destabilization | 23255108 | SIGNOR-276434 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| NEK1 | phosphorylation up-regulates → | VHL PSer168 | phosphorylation down-regulates ⊣ | VHL | 23255108 | SIGNOR-276434 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| NEK1 | phosphorylation down-regulates quantity by destabilization | VHL | SIGNOR-276434 |
