Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
Gbeta	ETV6	–		phosphorylation down-regulates	15060146	SIGNOR-270120
MAPK3	ETV6	Ser257 View in OncoXplorer	ESHPKPSsPRQESTR	phosphorylation down-regulates	15060146	SIGNOR-260085
ERK1/2	ETV6	Ser213 View in OncoXplorer	DNMIRRLsPAERAQG	phosphorylation down-regulates	15060146	SIGNOR-260084
MAPK1	ETV6	Ser213 View in OncoXplorer	DNMIRRLsPAERAQG	phosphorylation down-regulates	15060146	SIGNOR-260086
MAPK1	ETV6	Ser257 View in OncoXplorer	ESHPKPSsPRQESTR	phosphorylation down-regulates	15060146	SIGNOR-260087
PCSK7	ETV6	–		phosphorylation down-regulates	12435397	SIGNOR-95622
MAPK3	ETV6	Ser213 View in OncoXplorer	DNMIRRLsPAERAQG	phosphorylation down-regulates	15060146	SIGNOR-123656

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPK3	phosphorylation up-regulates →	ETV6 PSer257	phosphorylation down-regulates ⊣	ETV6	15060146	SIGNOR-260085
ERK1/2	phosphorylation up-regulates →	ETV6 PSer213	phosphorylation down-regulates ⊣	ETV6	15060146	SIGNOR-260084
MAPK1	phosphorylation up-regulates →	ETV6 PSer213	phosphorylation down-regulates ⊣	ETV6	15060146	SIGNOR-260086
MAPK1	phosphorylation up-regulates →	ETV6 PSer257	phosphorylation down-regulates ⊣	ETV6	15060146	SIGNOR-260087
MAPK3	phosphorylation up-regulates →	ETV6 PSer213	phosphorylation down-regulates ⊣	ETV6	15060146	SIGNOR-123656

Regulator	Mechanism/Effect	Target	SIGNOR-ID
Gbeta	phosphorylation down-regulates	ETV6	SIGNOR-270120
MAPK3	phosphorylation down-regulates	ETV6	SIGNOR-260085
ERK1/2	phosphorylation down-regulates	ETV6	SIGNOR-260084
MAPK1	phosphorylation down-regulates	ETV6	SIGNOR-260086
MAPK1	phosphorylation down-regulates	ETV6	SIGNOR-260087
PCSK7	phosphorylation down-regulates	ETV6	SIGNOR-95622
MAPK3	phosphorylation down-regulates	ETV6	SIGNOR-123656