| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | ETV6 | Ser213 | DNMIRRLsPAERAQG | phosphorylation down-regulates | 15060146 | SIGNOR-123656 |
| ERK1/2 | ETV6 | Ser213 | DNMIRRLsPAERAQG | phosphorylation down-regulates | 15060146 | SIGNOR-260084 |
| MAPK1 | ETV6 | Ser213 | DNMIRRLsPAERAQG | phosphorylation down-regulates | 15060146 | SIGNOR-260086 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | ETV6 PSer213 | phosphorylation down-regulates ⊣ | ETV6 | 15060146 | SIGNOR-123656 |
| ERK1/2 | phosphorylation up-regulates → | ETV6 PSer213 | phosphorylation down-regulates ⊣ | ETV6 | 15060146 | SIGNOR-260084 |
| MAPK1 | phosphorylation up-regulates → | ETV6 PSer213 | phosphorylation down-regulates ⊣ | ETV6 | 15060146 | SIGNOR-260086 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation![]() down-regulates | ETV6 | SIGNOR-123656 |
| ERK1/2 | phosphorylation![]() down-regulates | ETV6 | SIGNOR-260084 |
| MAPK1 | phosphorylation![]() down-regulates | ETV6 | SIGNOR-260086 |