| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | ETV6 | Ser257 | ESHPKPSsPRQESTR | phosphorylation down-regulates | 15060146 | SIGNOR-260087 |
| MAPK3 | ETV6 | Ser257 | ESHPKPSsPRQESTR | phosphorylation down-regulates | 15060146 | SIGNOR-260085 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | ETV6 PSer257 | phosphorylation down-regulates ⊣ | ETV6 | 15060146 | SIGNOR-260087 |
| MAPK3 | phosphorylation up-regulates → | ETV6 PSer257 | phosphorylation down-regulates ⊣ | ETV6 | 15060146 | SIGNOR-260085 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation![]() down-regulates | ETV6 | SIGNOR-260087 |
| MAPK3 | phosphorylation![]() down-regulates | ETV6 | SIGNOR-260085 |