Entity Details

Name AMPK_Ser303
ID P41235
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AMPKHNF4ASer303DPDAKGLsDPGKIKRphosphorylation
down-regulates		12740371SIGNOR-216511
AMPKHNF4ASer303DPDAKGLsDPGKIKRphosphorylation
down-regulates activity		12740371SIGNOR-263106
PRKAA1HNF4ASer303DPDAKGLsDPGKIKRphosphorylation
down-regulates activity		12740371SIGNOR-101101
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AMPKphosphorylation
up-regulates
→
HNF4A
PSer303		phosphorylation
down-regulates
⊣		HNF4A12740371SIGNOR-216511
AMPKphosphorylation
up-regulates
→
HNF4A
PSer303		phosphorylation
down-regulates
⊣		HNF4A12740371SIGNOR-263106
PRKAA1phosphorylation
up-regulates
→
HNF4A
PSer303		phosphorylation
down-regulates
⊣		HNF4A12740371SIGNOR-101101
Regulator Mechanism/Effect Target SIGNOR-ID
AMPKphosphorylation
img/direct_inhibition.png
down-regulates 		HNF4ASIGNOR-216511
AMPKphosphorylation
→
down-regulates activity 		HNF4ASIGNOR-263106
PRKAA1phosphorylation
→
down-regulates activity 		HNF4ASIGNOR-101101