| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | PPP1R2 | Ser87 | GDDEDACsDTEATEA | phosphorylation up-regulates activity | 8288648 | SIGNOR-250929 |
| CSNK2A1 | PPP1R2 | Ser121 | YRIQEQEsSGEEDSD | phosphorylation up-regulates | 9405437 | SIGNOR-53857 |
| CSNK2A2 | PPP1R2 | Ser87 | GDDEDACsDTEATEA | phosphorylation up-regulates activity | 8288648 | SIGNOR-251022 |
| CSNK2A2 | PPP1R2 | Ser122 | RIQEQESsGEEDSDL | phosphorylation up-regulates activity | 8288648 | SIGNOR-251021 |
| GSK3B | PPP1R2 | Thr73 | MKIDEPStPYHSMMG | phosphorylation up-regulates activity | 11320080 | SIGNOR-251257 |
| CSNK2A2 | PPP1R2 | Ser121 | YRIQEQEsSGEEDSD | phosphorylation up-regulates activity | 8288648 | SIGNOR-251020 |
| CSNK2A1 | PPP1R2 | Ser122 | RIQEQESsGEEDSDL | phosphorylation up-regulates | 9405437 | SIGNOR-53861 |
| CDK5 | PPP1R2 | Thr73 | MKIDEPStPYHSMMG | phosphorylation unknown | 11320080 | SIGNOR-250672 |
| ATM | PPP1R2 | Ser44 | DEELSKKsQKWDEMN | phosphorylation down-regulates | 18250156 | SIGNOR-160648 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | phosphorylation up-regulates → | PPP1R2 PSer87 | phosphorylation up-regulates → | PPP1R2 | 8288648 | SIGNOR-250929 |
| CSNK2A1 | phosphorylation up-regulates → | PPP1R2 PSer121 | phosphorylation up-regulates → | PPP1R2 | 9405437 | SIGNOR-53857 |
| CSNK2A2 | phosphorylation up-regulates → | PPP1R2 PSer87 | phosphorylation up-regulates → | PPP1R2 | 8288648 | SIGNOR-251022 |
| CSNK2A2 | phosphorylation up-regulates → | PPP1R2 PSer122 | phosphorylation up-regulates → | PPP1R2 | 8288648 | SIGNOR-251021 |
| GSK3B | phosphorylation up-regulates → | PPP1R2 PThr73 | phosphorylation up-regulates → | PPP1R2 | 11320080 | SIGNOR-251257 |
| CSNK2A2 | phosphorylation up-regulates → | PPP1R2 PSer121 | phosphorylation up-regulates → | PPP1R2 | 8288648 | SIGNOR-251020 |
| CSNK2A1 | phosphorylation up-regulates → | PPP1R2 PSer122 | phosphorylation up-regulates → | PPP1R2 | 9405437 | SIGNOR-53861 |
| CDK5 | phosphorylation up-regulates → | PPP1R2 PThr73 | phosphorylation down-regulates ⊣ | PPP1R2 | 11320080 | SIGNOR-250672 |
| ATM | phosphorylation up-regulates → | PPP1R2 PSer44 | phosphorylation down-regulates ⊣ | PPP1R2 | 18250156 | SIGNOR-160648 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A1 | phosphorylation → up-regulates activity | PPP1R2 | SIGNOR-250929 |
| CSNK2A1 | phosphorylation → up-regulates | PPP1R2 | SIGNOR-53857 |
| CSNK2A2 | phosphorylation → up-regulates activity | PPP1R2 | SIGNOR-251022 |
| CSNK2A2 | phosphorylation → up-regulates activity | PPP1R2 | SIGNOR-251021 |
| GSK3B | phosphorylation → up-regulates activity | PPP1R2 | SIGNOR-251257 |
| CSNK2A2 | phosphorylation → up-regulates activity | PPP1R2 | SIGNOR-251020 |
| CSNK2A1 | phosphorylation → up-regulates | PPP1R2 | SIGNOR-53861 |
| CDK5 | phosphorylation → unknown | PPP1R2 | SIGNOR-250672 |
| ATM | phosphorylation down-regulates | PPP1R2 | SIGNOR-160648 |
