| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | PPP1R2 | Thr73 | MKIDEPStPYHSMMG | phosphorylation up-regulates activity | 11320080 | SIGNOR-251257 |
| CDK5 | PPP1R2 | Thr73 | MKIDEPStPYHSMMG | phosphorylation unknown | 11320080 | SIGNOR-250672 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | PPP1R2 PThr73 | phosphorylation up-regulates → | PPP1R2 | 11320080 | SIGNOR-251257 |
| CDK5 | phosphorylation up-regulates → | PPP1R2 PThr73 | phosphorylation down-regulates ⊣ | PPP1R2 | 11320080 | SIGNOR-250672 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation → up-regulates activity | PPP1R2 | SIGNOR-251257 |
| CDK5 | phosphorylation → unknown | PPP1R2 | SIGNOR-250672 |
