Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CSK	LCK	Tyr505	FTATEGQyQPQP	phosphorylation down-regulates	1639064	SIGNOR-20371
CSK	LYN	Tyr508	YTATEGQyQQQP	phosphorylation down-regulates	15626731	SIGNOR-132912
CSK	PTPRC	Tyr1218	MVSTFEQyQFLYDVI	phosphorylation up-regulates	7507203	SIGNOR-26785
CSK	FGR	Tyr523	FTSAEPQyQPGDQT	phosphorylation down-regulates activity	7515063	SIGNOR-250779
CSK	SRC	Tyr530	FTSTEPQyQPGENL	phosphorylation down-regulates	18614016	SIGNOR-179417
CSK	EEF2	–		phosphorylation down-regulates quantity	24648518	SIGNOR-279698
CSK	PECAM1	Tyr713	KKDTETVySEVRKAV	phosphorylation up-regulates activity	9624175	SIGNOR-262741
CSK	CSK	Tyr304	DVCEAMEyLEGNNFV	phosphorylation up-regulates activity	9148770	SIGNOR-250778
CSK	MDM2	Tyr281	EVYQVTVyQAGESDT	phosphorylation up-regulates activity	25624478	SIGNOR-279163
CSK	MDM2	Tyr302	PEISLADyWKCTSCN	phosphorylation up-regulates activity	25624478	SIGNOR-279164
CSK	ITCH	–		phosphorylation down-regulates activity	16888620	SIGNOR-245327

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CSK	phosphorylation up-regulates →	LCK PTyr505	phosphorylation down-regulates ⊣	LCK	1639064	SIGNOR-20371
CSK	phosphorylation up-regulates →	LYN PTyr508	phosphorylation down-regulates ⊣	LYN	15626731	SIGNOR-132912
CSK	phosphorylation up-regulates →	PTPRC PTyr1218	phosphorylation up-regulates →	PTPRC	7507203	SIGNOR-26785
CSK	phosphorylation up-regulates →	FGR PTyr523	phosphorylation down-regulates ⊣	FGR	7515063	SIGNOR-250779
CSK	phosphorylation up-regulates →	SRC PTyr530	phosphorylation down-regulates ⊣	SRC	18614016	SIGNOR-179417
CSK	phosphorylation up-regulates →	PECAM1 PTyr713	phosphorylation up-regulates →	PECAM1	9624175	SIGNOR-262741
CSK	phosphorylation up-regulates →	CSK PTyr304	phosphorylation up-regulates →	CSK	9148770	SIGNOR-250778
CSK	phosphorylation up-regulates →	MDM2 PTyr281	phosphorylation up-regulates →	MDM2	25624478	SIGNOR-279163
CSK	phosphorylation up-regulates →	MDM2 PTyr302	phosphorylation up-regulates →	MDM2	25624478	SIGNOR-279164

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CSK	phosphorylation down-regulates	LCK	SIGNOR-20371
CSK	phosphorylation down-regulates	LYN	SIGNOR-132912
CSK	phosphorylation → up-regulates	PTPRC	SIGNOR-26785
CSK	phosphorylation → down-regulates activity	FGR	SIGNOR-250779
CSK	phosphorylation down-regulates	SRC	SIGNOR-179417
CSK	phosphorylation → down-regulates quantity	EEF2	SIGNOR-279698
CSK	phosphorylation → up-regulates activity	PECAM1	SIGNOR-262741
CSK	phosphorylation → up-regulates activity	CSK	SIGNOR-250778
CSK	phosphorylation → up-regulates activity	MDM2	SIGNOR-279163
CSK	phosphorylation → up-regulates activity	MDM2	SIGNOR-279164
CSK	phosphorylation → down-regulates activity	ITCH	SIGNOR-245327