Entity Details

Name CSK
ID P41240
Role substrate
Enzymatic Domains
SH2 82-171
PROSITE-ProRule
Protein kinase 195-449
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CSKCSKTyr304DVCEAMEyLEGNNFVphosphorylation
up-regulates activity		9148770SIGNOR-250778
PRKACACSKSer364ALREKKFsTKSDVWSphosphorylation
up-regulates activity		11181701SIGNOR-105229
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSKphosphorylation
up-regulates
→
CSK
PTyr304		phosphorylation
up-regulates
→		CSK9148770SIGNOR-250778
PRKACAphosphorylation
up-regulates
→
CSK
PSer364		phosphorylation
up-regulates
→		CSK11181701SIGNOR-105229
Regulator Mechanism/Effect Target SIGNOR-ID
CSKphosphorylation
→
up-regulates activity 		CSKSIGNOR-250778
PRKACAphosphorylation
→
up-regulates activity 		CSKSIGNOR-105229