| Name | EPS15 |
| ID | P42566 |
| Role | substrate |
| Enzymatic Domains |
EH 1 15-104 PROSITE-ProRule
EF-hand 1 48-83 PROSITE-ProRule
EH 2 128-216 PROSITE-ProRule
EF-hand 2 160-195 PROSITE-ProRule
EF-hand 3 223-258 PROSITE-ProRule
EH 3 224-314 PROSITE-ProRule
EF-hand 4 262-292 PROSITE-ProRule
UIM 1 851-870 PROSITE-ProRule
UIM 2 877-896 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | EPS15 | Tyr849 | NFANFSAyPSEEDMI | phosphorylation up-regulates | 24269888 | SIGNOR-203311 |
| MAPK14 | EPS15 | Ser796 | RSINKLDsPDPFKLN | phosphorylation up-regulates | 24269888 | SIGNOR-203315 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | phosphorylation up-regulates → | EPS15 PTyr849 | phosphorylation up-regulates → | EPS15 | 24269888 | SIGNOR-203311 |
| MAPK14 | phosphorylation up-regulates → | EPS15 PSer796 | phosphorylation up-regulates → | EPS15 | 24269888 | SIGNOR-203315 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EGFR | phosphorylation → up-regulates | EPS15 | SIGNOR-203311 |
| MAPK14 | phosphorylation → up-regulates | EPS15 | SIGNOR-203315 |