| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ITK | TEC | Tyr206 | RLERGQEyLILEKND | phosphorylation up-regulates | 12573241 | SIGNOR-98090 |
| BTK | TEC | Tyr206 | RLERGQEyLILEKND | phosphorylation up-regulates | 12573241 | SIGNOR-98086 |
| TEC | TEC | Tyr206 | RLERGQEyLILEKND | phosphorylation up-regulates | 12573241 | SIGNOR-98098 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ITK | phosphorylation up-regulates → | TEC PTyr206 | phosphorylation up-regulates → | TEC | 12573241 | SIGNOR-98090 |
| BTK | phosphorylation up-regulates → | TEC PTyr206 | phosphorylation up-regulates → | TEC | 12573241 | SIGNOR-98086 |
| TEC | phosphorylation up-regulates → | TEC PTyr206 | phosphorylation up-regulates → | TEC | 12573241 | SIGNOR-98098 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ITK | phosphorylation → up-regulates | TEC | SIGNOR-98090 |
| BTK | phosphorylation → up-regulates | TEC | SIGNOR-98086 |
| TEC | phosphorylation → up-regulates | TEC | SIGNOR-98098 |
