Entity Details

Name TXK
ID P42681
Role kinase
Enzymatic Domains
SH3 82-142
PROSITE-ProRule
SH2 150-246
PROSITE-ProRule
Protein kinase 271-527
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TXKCTLA4Tyr201SPLTTGVyVKMPPTEphosphorylation
up-regulates quantity by stabilization
9813138SIGNOR-61624
TXKTXKTyr91KIQVKALyDFLPREPphosphorylation
up-regulates
12081135SIGNOR-89844
TXKLCP2Tyr113SSFEEDDyESPNDDQphosphorylation
up-regulates
10660534SIGNOR-74844
TXKLCP2Tyr145PVEDDADyEPPPSNDphosphorylation
up-regulates
10660534SIGNOR-74848
TXKLCP2Tyr113SSFEEDDyESPNDDQphosphorylation
up-regulates
8892604SIGNOR-44665
TXKLCP2Tyr145PVEDDADyEPPPSNDphosphorylation
up-regulates
8892604SIGNOR-44669
TXKLCP2Tyr128DGEDDGDyESPNEEEphosphorylation
up-regulates activity
10660534SIGNOR-246929
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TXKphosphorylation
up-regulates
CTLA4
PTyr201
phosphorylation
up-regulates
CTLA49813138SIGNOR-61624
TXKphosphorylation
up-regulates
TXK
PTyr91
phosphorylation
up-regulates
TXK12081135SIGNOR-89844
TXKphosphorylation
up-regulates
LCP2
PTyr113
phosphorylation
up-regulates
LCP210660534SIGNOR-74844
TXKphosphorylation
up-regulates
LCP2
PTyr145
phosphorylation
up-regulates
LCP210660534SIGNOR-74848
TXKphosphorylation
up-regulates
LCP2
PTyr113
phosphorylation
up-regulates
LCP28892604SIGNOR-44665
TXKphosphorylation
up-regulates
LCP2
PTyr145
phosphorylation
up-regulates
LCP28892604SIGNOR-44669
TXKphosphorylation
up-regulates
LCP2
PTyr128
phosphorylation
up-regulates
LCP210660534SIGNOR-246929
Regulator Mechanism/Effect Target SIGNOR-ID
TXKphosphorylation

up-regulates quantity by stabilization
CTLA4SIGNOR-61624
TXKphosphorylation

up-regulates
TXKSIGNOR-89844
TXKphosphorylation

up-regulates
LCP2SIGNOR-74844
TXKphosphorylation

up-regulates
LCP2SIGNOR-74848
TXKphosphorylation

up-regulates
LCP2SIGNOR-44665
TXKphosphorylation

up-regulates
LCP2SIGNOR-44669
TXKphosphorylation

up-regulates activity
LCP2SIGNOR-246929