Entity Details

Name TXK
ID P42681
Role substrate
Enzymatic Domains
SH3 82-142
PROSITE-ProRule
SH2 150-246
PROSITE-ProRule
Protein kinase 271-527
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCTXKTyr420RYVLDDEyVSSFGAKphosphorylation
up-regulates activity		11353545SIGNOR-247346
TXKTXKTyr91KIQVKALyDFLPREPphosphorylation
up-regulates		12081135SIGNOR-89844
FYNTXKTyr420RYVLDDEyVSSFGAKphosphorylation
up-regulates activity		11353545SIGNOR-249341
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
TXK
PTyr420		phosphorylation
up-regulates
→		TXK11353545SIGNOR-247346
TXKphosphorylation
up-regulates
→
TXK
PTyr91		phosphorylation
up-regulates
→		TXK12081135SIGNOR-89844
FYNphosphorylation
up-regulates
→
TXK
PTyr420		phosphorylation
up-regulates
→		TXK11353545SIGNOR-249341
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		TXKSIGNOR-247346
TXKphosphorylation
→
up-regulates 		TXKSIGNOR-89844
FYNphosphorylation
→
up-regulates activity 		TXKSIGNOR-249341