| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | MTHFR | Thr34 | KDSSRCStPGLDPER | phosphorylation down-regulates activity | 24769206 | SIGNOR-263888 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | MTHFR PThr34 | phosphorylation down-regulates ⊣ | MTHFR | 24769206 | SIGNOR-263888 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation → down-regulates activity | MTHFR | SIGNOR-263888 |
