Entity Details

Name DCC
ID P43146
Role substrate
Enzymatic Domains
Ig-like C2-type 1 26-135
Ig-like C2-type 2 139-229
Ig-like C2-type 3 234-326
Ig-like C2-type 4 331-416
Fibronectin type-III 1 431-524
PROSITE-ProRule
Fibronectin type-III 2 530-620
PROSITE-ProRule
Fibronectin type-III 3 625-718
PROSITE-ProRule
Fibronectin type-III 4 728-821
PROSITE-ProRule
Fibronectin type-III 5 846-942
PROSITE-ProRule
Fibronectin type-III 6 947-1044
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
FYNDCCTyr1420TEDSANVyEQDDLSEphosphorylation
up-regulates activity		15557120SIGNOR-268176
FYNDCCTyr1261PTLESAQyPGILPSPphosphorylation
up-regulates activity		15557120SIGNOR-268175
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
FYNphosphorylation
up-regulates
→
DCC
PTyr1420		phosphorylation
up-regulates
→		DCC15557120SIGNOR-268176
FYNphosphorylation
up-regulates
→
DCC
PTyr1261		phosphorylation
up-regulates
→		DCC15557120SIGNOR-268175
Regulator Mechanism/Effect Target SIGNOR-ID
FYNphosphorylation
→
up-regulates activity 		DCCSIGNOR-268176
FYNphosphorylation
→
up-regulates activity 		DCCSIGNOR-268175