| Name | GRK6 |
| ID | P43250 |
| Role | substrate |
| Enzymatic Domains |
RGS 53-171 PROSITE-ProRule
Protein kinase 186-448 PROSITE-ProRule
AGC-kinase C-terminal 449-514 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GRK6 | GRK6 | Ser484 | VLDIEQFsTVKGVEL | phosphorylation unknown | 10334944 | SIGNOR-251211 |
| GRK6 | GRK6 | Thr485 | LDIEQFStVKGVELE | phosphorylation unknown | 10334944 | SIGNOR-251212 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GRK6 | phosphorylation up-regulates → | GRK6 PSer484 | phosphorylation down-regulates ⊣ | GRK6 | 10334944 | SIGNOR-251211 |
| GRK6 | phosphorylation up-regulates → | GRK6 PThr485 | phosphorylation down-regulates ⊣ | GRK6 | 10334944 | SIGNOR-251212 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GRK6 | phosphorylation → unknown | GRK6 | SIGNOR-251211 |
| GRK6 | phosphorylation → unknown | GRK6 | SIGNOR-251212 |