| Name | SYK |
| ID | P43405 |
| Role | kinase |
| Enzymatic Domains |
SH2 1 15-107 PROSITE-ProRule
SH2 2 168-259 PROSITE-ProRule
Protein kinase 371-631 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SYK | CGAS | Tyr214 | GLLNTGSyYEHVKIS | phosphorylation up-regulates activity | 36252040 | SIGNOR-277844 |
| SYK | LRRFIP1 | – | phosphorylation up-regulates activity | 19151749 | SIGNOR-279297 | |
| SYK | SLC4A1 | Tyr8 | MEELQDDyEDMMEEN | phosphorylation unknown | 10942405 | SIGNOR-251413 |
| SYK | PAX5 | – | phosphorylation down-regulates activity | 27181361 | SIGNOR-269084 | |
| SYK | BTK | Tyr551 | RYVLDDEyTSSVGSK | phosphorylation up-regulates activity | 11226282 | SIGNOR-247586 |
| SYK | PIP5K1B | Tyr105 | FGIKPDDyLYSICSE | phosphorylation down-regulates activity | 19553680 | SIGNOR-276227 |
| SYK | SYK | Tyr526 | LRADENYyKAQTHGK | phosphorylation up-regulates activity | 9820500 | SIGNOR-246621 |
| SYK | IKZF1 | Ser361 | LAEGTPRsNHSAQDS | phosphorylation up-regulates | 23071339 | SIGNOR-199096 |
| SYK | BLNK | Tyr72 | SDDFDSDyENPDEHS | phosphorylation up-regulates | 12456653 | SIGNOR-96044 |
| SYK | PRKCA | Tyr658 | SDFEGFSyVNPQFVH | phosphorylation up-regulates activity | 12881490 | SIGNOR-246581 |
| SYK | HCLS1 | Tyr378 | EPEPENDyEDVEEMD | phosphorylation up-regulates | 9104825 | SIGNOR-47338 |
| SYK | PLCG1 | Tyr783 | EGRNPGFyVEANPMP | phosphorylation up-regulates activity | 8657103 | SIGNOR-246576 |
| SYK | LCK | Tyr192 | NLDNGGFyISPRITF | phosphorylation down-regulates activity | 8798764 | SIGNOR-246562 |
| SYK | PLCG2 | – | phosphorylation up-regulates activity | 25955968 | SIGNOR-278995 | |
| SYK | SYK | Tyr352 | TEVYESPyADPEEIR | phosphorylation up-regulates activity | 9820500 | SIGNOR-246613 |
| SYK | BLNK | Tyr96 | EENADDSyEPPPVEQ | phosphorylation up-regulates | 12456653 | SIGNOR-96052 |
| SYK | LAX1 | Tyr294 | AFQCCRDyENVPAAD | phosphorylation up-regulates activity | 12359715 | SIGNOR-273534 |
| SYK | IL15RA | Tyr227 | AVSLLACyLKSRQTP | phosphorylation up-regulates activity | 11714793 | SIGNOR-246556 |
| SYK | FCGR2A | Tyr281 | LEETNNDyETADGGY | phosphorylation up-regulates activity | 8756631 | SIGNOR-247590 |
| SYK | SYK | Tyr525 | ALRADENyYKAQTHG | phosphorylation up-regulates activity | 9820500 | SIGNOR-246617 |
| SYK | STAT3 | – | phosphorylation up-regulates activity | 26848618 | SIGNOR-279298 | |
| SYK | USP25 | Tyr740 | QAAGDPEyLEQPSRS | phosphorylation down-regulates quantity | 19909739 | SIGNOR-278458 |
| SYK | FLT3 | Tyr768 | HSEDEIEyENQKRLE | phosphorylation up-regulates activity | 24525236 | SIGNOR-278431 |
| SYK | SNCA | Tyr125 | VDPDNEAyEMPSEEG | phosphorylation down-regulates | 11744621 | SIGNOR-113061 |
| SYK | GCSAM | Tyr106 | SGNSAEEyYENVPCK | phosphorylation up-regulates activity | 31362927 | SIGNOR-273570 |
| SYK | LAT2 | Tyr233 | EEDGEPDyVNGEVAA | phosphorylation up-regulates activity | 14722116 | SIGNOR-273577 |
| SYK | LAX1 | Tyr193 | SSEDSHDyVNVPTAE | phosphorylation up-regulates activity | 12359715 | SIGNOR-273532 |
| SYK | SH3BP2 | Tyr174 | YPTDNEDyEHDDEDD | phosphorylation up-regulates activity | 12709437 | SIGNOR-246587 |
| SYK | FCGR2A | Tyr304 | TDDDKNIyLTLPPND | phosphorylation up-regulates activity | 8756631 | SIGNOR-246551 |
| SYK | HCLS1 | Tyr397 | EDEPEGDyEEVLEPE | phosphorylation up-regulates | 9104825 | SIGNOR-47342 |
| SYK | DEPTOR | Tyr289 | SSCGSSGyFSSSPTL | phosphorylation down-regulates activity | 34634301 | SIGNOR-277572 |
| SYK | BLNK | Tyr178 | LLEDEADyVVPVEDN | phosphorylation up-regulates | 12456653 | SIGNOR-96040 |
| SYK | SLC4A1 | Tyr21 | ENLEQEEyEDPDIPE | phosphorylation unknown | 10942405 | SIGNOR-251411 |
| SYK | HUWE1 | – | phosphorylation up-regulates activity | 26212014 | SIGNOR-280150 | |
| SYK | MAPT | Tyr18 | MEDHAGTyGLGDRKD | phosphorylation down-regulates | 18070606 | SIGNOR-159648 |
| SYK | GCSAM | Tyr80 | QDNVDQTySEELCYT | phosphorylation up-regulates activity | 31362927 | SIGNOR-273572 |
| SYK | SYK | Tyr323 | STVSFNPyEPELAPW | phosphorylation up-regulates activity | 9820500 | SIGNOR-246605 |
| SYK | EZR | – | phosphorylation up-regulates activity | 23703860 | SIGNOR-279129 | |
| SYK | MAP4K1 | Tyr381 | SESSDDDyDDVDIPT | phosphorylation up-regulates activity | 11514608 | SIGNOR-246567 |
| SYK | GCSAM | Tyr128 | LGGTETEySLLHMPS | phosphorylation up-regulates activity | 31362927 | SIGNOR-273573 |
| SYK | DUSP3 | Tyr138 | SPTLVIAyLMMRQKM | phosphorylation up-regulates activity | 12447358 | SIGNOR-275999 |
| SYK | SHC1 | Tyr349 | EEPPDHQyYNDFPGK | phosphorylation up-regulates | 9710204 | SIGNOR-59635 |
| SYK | LAT2 | Tyr193 | EDEESEDyQNSASIH | phosphorylation up-regulates activity | 14722116 | SIGNOR-273575 |
| SYK | IKZF1 | Ser364 | GTPRSNHsAQDSAVE | phosphorylation up-regulates | 23071339 | SIGNOR-199100 |
| SYK | SNCA | Tyr136 | SEEGYQDyEPEA | phosphorylation down-regulates | 11744621 | SIGNOR-113069 |
| SYK | PLCG1 | Tyr771 | IGTAEPDyGALYEGR | phosphorylation up-regulates activity | 8657103 | SIGNOR-246572 |
| SYK | TUBA4A | Tyr432 | MAALEKDyEEVGIDS | phosphorylation up-regulates activity | 9490415 | SIGNOR-246626 |
| SYK | FCGR2C | Tyr287 | PEETNNDyETADGGY | phosphorylation up-regulates activity | 8756631 | SIGNOR-262674 |
| SYK | FCGR2C | Tyr310 | TDDDKNIyLTLPPND | phosphorylation up-regulates activity | 8756631 | SIGNOR-262675 |
| SYK | GCSAM | Tyr107 | GNSAEEYyENVPCKA | phosphorylation up-regulates activity | 31362927 | SIGNOR-273571 |
| SYK | VAV1 | – | phosphorylation up-regulates | 11331248 | SIGNOR-107046 | |
| SYK | CDC25C | Ser216 | SGLYRSPsMPENLNR | phosphorylation down-regulates activity | 25506060 | SIGNOR-278328 |
| SYK | SHC1 | Tyr350 | EPPDHQYyNDFPGKE | phosphorylation up-regulates | 9710204 | SIGNOR-59639 |
| SYK | SLC4A1 | Tyr21 | ENLEQEEyEDPDIPE | phosphorylation up-regulates | 10942405 | SIGNOR-80788 |
| SYK | FLT3 | Tyr955 | ADAEEAMyQNVDGRV | phosphorylation up-regulates activity | 24525236 | SIGNOR-278430 |
| SYK | GCSAM | Tyr86 | TYSEELCyTLINHRV | phosphorylation up-regulates activity | 31362927 | SIGNOR-273574 |
| SYK | SYK | Tyr131 | KENLIREyVKQTWNL | phosphorylation up-regulates activity | 9820500 | SIGNOR-246601 |
| SYK | LAX1 | Tyr373 | SNEDSSDyENVLTAK | phosphorylation up-regulates activity | 12359715 | SIGNOR-273535 |
| SYK | BLNK | Tyr84 | EHSDSEMyVMPAEEN | phosphorylation up-regulates | 12456653 | SIGNOR-96048 |
| SYK | SNCA | Tyr133 | EMPSEEGyQDYEPEA | phosphorylation down-regulates | 11744621 | SIGNOR-113065 |
| SYK | SH3BP2 | Tyr448 | GDDSDEDyEKVPLPN | phosphorylation up-regulates activity | 12709437 | SIGNOR-246596 |
| SYK | SH3BP2 | Tyr183 | HDDEDDSyLEPDSPE | phosphorylation up-regulates activity | 12709437 | SIGNOR-246592 |
| SYK | LAX1 | Tyr268 | SSQISNDyVNMTGLD | phosphorylation up-regulates activity | 12359715 | SIGNOR-273533 |
| SYK | SLC4A1 | Tyr8 | MEELQDDyEDMMEEN | phosphorylation up-regulates | 10942405 | SIGNOR-80792 |
| SYK | CGAS | Tyr215 | LLNTGSYyEHVKISA | phosphorylation up-regulates activity | 36252040 | SIGNOR-277845 |
| SYK | SYK | Tyr348 | LPMDTEVyESPYADP | phosphorylation up-regulates activity | 9820500 | SIGNOR-246609 |
| SYK | LAT2 | Tyr136 | EDDDANSyENVLICK | phosphorylation up-regulates activity | 14722116 | SIGNOR-273576 |
| SYK | SHC1 | Tyr427 | ELFDDPSyVNVQNLD | phosphorylation up-regulates | 9710204 | SIGNOR-59643 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SYK | phosphorylation up-regulates → | CGAS PTyr214 | phosphorylation up-regulates → | CGAS | 36252040 | SIGNOR-277844 |
| SYK | phosphorylation up-regulates → | SLC4A1 PTyr8 | phosphorylation down-regulates ⊣ | SLC4A1 | 10942405 | SIGNOR-251413 |
| SYK | phosphorylation up-regulates → | BTK PTyr551 | phosphorylation up-regulates → | BTK | 11226282 | SIGNOR-247586 |
| SYK | phosphorylation up-regulates → | PIP5K1B PTyr105 | phosphorylation down-regulates ⊣ | PIP5K1B | 19553680 | SIGNOR-276227 |
| SYK | phosphorylation up-regulates → | SYK PTyr526 | phosphorylation up-regulates → | SYK | 9820500 | SIGNOR-246621 |
| SYK | phosphorylation up-regulates → | IKZF1 PSer361 | phosphorylation up-regulates → | IKZF1 | 23071339 | SIGNOR-199096 |
| SYK | phosphorylation up-regulates → | BLNK PTyr72 | phosphorylation up-regulates → | BLNK | 12456653 | SIGNOR-96044 |
| SYK | phosphorylation up-regulates → | PRKCA PTyr658 | phosphorylation up-regulates → | PRKCA | 12881490 | SIGNOR-246581 |
| SYK | phosphorylation up-regulates → | HCLS1 PTyr378 | phosphorylation up-regulates → | HCLS1 | 9104825 | SIGNOR-47338 |
| SYK | phosphorylation up-regulates → | PLCG1 PTyr783 | phosphorylation up-regulates → | PLCG1 | 8657103 | SIGNOR-246576 |
| SYK | phosphorylation up-regulates → | LCK PTyr192 | phosphorylation down-regulates ⊣ | LCK | 8798764 | SIGNOR-246562 |
| SYK | phosphorylation up-regulates → | SYK PTyr352 | phosphorylation up-regulates → | SYK | 9820500 | SIGNOR-246613 |
| SYK | phosphorylation up-regulates → | BLNK PTyr96 | phosphorylation up-regulates → | BLNK | 12456653 | SIGNOR-96052 |
| SYK | phosphorylation up-regulates → | LAX1 PTyr294 | phosphorylation up-regulates → | LAX1 | 12359715 | SIGNOR-273534 |
| SYK | phosphorylation up-regulates → | IL15RA PTyr227 | phosphorylation up-regulates → | IL15RA | 11714793 | SIGNOR-246556 |
| SYK | phosphorylation up-regulates → | FCGR2A PTyr281 | phosphorylation up-regulates → | FCGR2A | 8756631 | SIGNOR-247590 |
| SYK | phosphorylation up-regulates → | SYK PTyr525 | phosphorylation up-regulates → | SYK | 9820500 | SIGNOR-246617 |
| SYK | phosphorylation up-regulates → | USP25 PTyr740 | phosphorylation down-regulates ⊣ | USP25 | 19909739 | SIGNOR-278458 |
| SYK | phosphorylation up-regulates → | FLT3 PTyr768 | phosphorylation up-regulates → | FLT3 | 24525236 | SIGNOR-278431 |
| SYK | phosphorylation up-regulates → | SNCA PTyr125 | phosphorylation down-regulates ⊣ | SNCA | 11744621 | SIGNOR-113061 |
| SYK | phosphorylation up-regulates → | GCSAM PTyr106 | phosphorylation up-regulates → | GCSAM | 31362927 | SIGNOR-273570 |
| SYK | phosphorylation up-regulates → | LAT2 PTyr233 | phosphorylation up-regulates → | LAT2 | 14722116 | SIGNOR-273577 |
| SYK | phosphorylation up-regulates → | LAX1 PTyr193 | phosphorylation up-regulates → | LAX1 | 12359715 | SIGNOR-273532 |
| SYK | phosphorylation up-regulates → | SH3BP2 PTyr174 | phosphorylation up-regulates → | SH3BP2 | 12709437 | SIGNOR-246587 |
| SYK | phosphorylation up-regulates → | FCGR2A PTyr304 | phosphorylation up-regulates → | FCGR2A | 8756631 | SIGNOR-246551 |
| SYK | phosphorylation up-regulates → | HCLS1 PTyr397 | phosphorylation up-regulates → | HCLS1 | 9104825 | SIGNOR-47342 |
| SYK | phosphorylation up-regulates → | DEPTOR PTyr289 | phosphorylation down-regulates ⊣ | DEPTOR | 34634301 | SIGNOR-277572 |
| SYK | phosphorylation up-regulates → | BLNK PTyr178 | phosphorylation up-regulates → | BLNK | 12456653 | SIGNOR-96040 |
| SYK | phosphorylation up-regulates → | SLC4A1 PTyr21 | phosphorylation down-regulates ⊣ | SLC4A1 | 10942405 | SIGNOR-251411 |
| SYK | phosphorylation up-regulates → | MAPT PTyr18 | phosphorylation down-regulates ⊣ | MAPT | 18070606 | SIGNOR-159648 |
| SYK | phosphorylation up-regulates → | GCSAM PTyr80 | phosphorylation up-regulates → | GCSAM | 31362927 | SIGNOR-273572 |
| SYK | phosphorylation up-regulates → | SYK PTyr323 | phosphorylation up-regulates → | SYK | 9820500 | SIGNOR-246605 |
| SYK | phosphorylation up-regulates → | MAP4K1 PTyr381 | phosphorylation up-regulates → | MAP4K1 | 11514608 | SIGNOR-246567 |
| SYK | phosphorylation up-regulates → | GCSAM PTyr128 | phosphorylation up-regulates → | GCSAM | 31362927 | SIGNOR-273573 |
| SYK | phosphorylation up-regulates → | DUSP3 PTyr138 | phosphorylation up-regulates → | DUSP3 | 12447358 | SIGNOR-275999 |
| SYK | phosphorylation up-regulates → | SHC1 PTyr349 | phosphorylation up-regulates → | SHC1 | 9710204 | SIGNOR-59635 |
| SYK | phosphorylation up-regulates → | LAT2 PTyr193 | phosphorylation up-regulates → | LAT2 | 14722116 | SIGNOR-273575 |
| SYK | phosphorylation up-regulates → | IKZF1 PSer364 | phosphorylation up-regulates → | IKZF1 | 23071339 | SIGNOR-199100 |
| SYK | phosphorylation up-regulates → | SNCA PTyr136 | phosphorylation down-regulates ⊣ | SNCA | 11744621 | SIGNOR-113069 |
| SYK | phosphorylation up-regulates → | PLCG1 PTyr771 | phosphorylation up-regulates → | PLCG1 | 8657103 | SIGNOR-246572 |
| SYK | phosphorylation up-regulates → | TUBA4A PTyr432 | phosphorylation up-regulates → | TUBA4A | 9490415 | SIGNOR-246626 |
| SYK | phosphorylation up-regulates → | FCGR2C PTyr287 | phosphorylation up-regulates → | FCGR2C | 8756631 | SIGNOR-262674 |
| SYK | phosphorylation up-regulates → | FCGR2C PTyr310 | phosphorylation up-regulates → | FCGR2C | 8756631 | SIGNOR-262675 |
| SYK | phosphorylation up-regulates → | GCSAM PTyr107 | phosphorylation up-regulates → | GCSAM | 31362927 | SIGNOR-273571 |
| SYK | phosphorylation up-regulates → | CDC25C PSer216 | phosphorylation down-regulates ⊣ | CDC25C | 25506060 | SIGNOR-278328 |
| SYK | phosphorylation up-regulates → | SHC1 PTyr350 | phosphorylation up-regulates → | SHC1 | 9710204 | SIGNOR-59639 |
| SYK | phosphorylation up-regulates → | SLC4A1 PTyr21 | phosphorylation up-regulates → | SLC4A1 | 10942405 | SIGNOR-80788 |
| SYK | phosphorylation up-regulates → | FLT3 PTyr955 | phosphorylation up-regulates → | FLT3 | 24525236 | SIGNOR-278430 |
| SYK | phosphorylation up-regulates → | GCSAM PTyr86 | phosphorylation up-regulates → | GCSAM | 31362927 | SIGNOR-273574 |
| SYK | phosphorylation up-regulates → | SYK PTyr131 | phosphorylation up-regulates → | SYK | 9820500 | SIGNOR-246601 |
| SYK | phosphorylation up-regulates → | LAX1 PTyr373 | phosphorylation up-regulates → | LAX1 | 12359715 | SIGNOR-273535 |
| SYK | phosphorylation up-regulates → | BLNK PTyr84 | phosphorylation up-regulates → | BLNK | 12456653 | SIGNOR-96048 |
| SYK | phosphorylation up-regulates → | SNCA PTyr133 | phosphorylation down-regulates ⊣ | SNCA | 11744621 | SIGNOR-113065 |
| SYK | phosphorylation up-regulates → | SH3BP2 PTyr448 | phosphorylation up-regulates → | SH3BP2 | 12709437 | SIGNOR-246596 |
| SYK | phosphorylation up-regulates → | SH3BP2 PTyr183 | phosphorylation up-regulates → | SH3BP2 | 12709437 | SIGNOR-246592 |
| SYK | phosphorylation up-regulates → | LAX1 PTyr268 | phosphorylation up-regulates → | LAX1 | 12359715 | SIGNOR-273533 |
| SYK | phosphorylation up-regulates → | SLC4A1 PTyr8 | phosphorylation up-regulates → | SLC4A1 | 10942405 | SIGNOR-80792 |
| SYK | phosphorylation up-regulates → | CGAS PTyr215 | phosphorylation up-regulates → | CGAS | 36252040 | SIGNOR-277845 |
| SYK | phosphorylation up-regulates → | SYK PTyr348 | phosphorylation up-regulates → | SYK | 9820500 | SIGNOR-246609 |
| SYK | phosphorylation up-regulates → | LAT2 PTyr136 | phosphorylation up-regulates → | LAT2 | 14722116 | SIGNOR-273576 |
| SYK | phosphorylation up-regulates → | SHC1 PTyr427 | phosphorylation up-regulates → | SHC1 | 9710204 | SIGNOR-59643 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SYK | phosphorylation → up-regulates activity | CGAS | SIGNOR-277844 |
| SYK | phosphorylation → up-regulates activity | LRRFIP1 | SIGNOR-279297 |
| SYK | phosphorylation → unknown | SLC4A1 | SIGNOR-251413 |
| SYK | phosphorylation → down-regulates activity | PAX5 | SIGNOR-269084 |
| SYK | phosphorylation → up-regulates activity | BTK | SIGNOR-247586 |
| SYK | phosphorylation → down-regulates activity | PIP5K1B | SIGNOR-276227 |
| SYK | phosphorylation → up-regulates activity | SYK | SIGNOR-246621 |
| SYK | phosphorylation → up-regulates | IKZF1 | SIGNOR-199096 |
| SYK | phosphorylation → up-regulates | BLNK | SIGNOR-96044 |
| SYK | phosphorylation → up-regulates activity | PRKCA | SIGNOR-246581 |
| SYK | phosphorylation → up-regulates | HCLS1 | SIGNOR-47338 |
| SYK | phosphorylation → up-regulates activity | PLCG1 | SIGNOR-246576 |
| SYK | phosphorylation → down-regulates activity | LCK | SIGNOR-246562 |
| SYK | phosphorylation → up-regulates activity | PLCG2 | SIGNOR-278995 |
| SYK | phosphorylation → up-regulates activity | SYK | SIGNOR-246613 |
| SYK | phosphorylation → up-regulates | BLNK | SIGNOR-96052 |
| SYK | phosphorylation → up-regulates activity | LAX1 | SIGNOR-273534 |
| SYK | phosphorylation → up-regulates activity | IL15RA | SIGNOR-246556 |
| SYK | phosphorylation → up-regulates activity | FCGR2A | SIGNOR-247590 |
| SYK | phosphorylation → up-regulates activity | SYK | SIGNOR-246617 |
| SYK | phosphorylation → up-regulates activity | STAT3 | SIGNOR-279298 |
| SYK | phosphorylation → down-regulates quantity | USP25 | SIGNOR-278458 |
| SYK | phosphorylation → up-regulates activity | FLT3 | SIGNOR-278431 |
| SYK | phosphorylation down-regulates | SNCA | SIGNOR-113061 |
| SYK | phosphorylation → up-regulates activity | GCSAM | SIGNOR-273570 |
| SYK | phosphorylation → up-regulates activity | LAT2 | SIGNOR-273577 |
| SYK | phosphorylation → up-regulates activity | LAX1 | SIGNOR-273532 |
| SYK | phosphorylation → up-regulates activity | SH3BP2 | SIGNOR-246587 |
| SYK | phosphorylation → up-regulates activity | FCGR2A | SIGNOR-246551 |
| SYK | phosphorylation → up-regulates | HCLS1 | SIGNOR-47342 |
| SYK | phosphorylation → down-regulates activity | DEPTOR | SIGNOR-277572 |
| SYK | phosphorylation → up-regulates | BLNK | SIGNOR-96040 |
| SYK | phosphorylation → unknown | SLC4A1 | SIGNOR-251411 |
| SYK | phosphorylation → up-regulates activity | HUWE1 | SIGNOR-280150 |
| SYK | phosphorylation down-regulates | MAPT | SIGNOR-159648 |
| SYK | phosphorylation → up-regulates activity | GCSAM | SIGNOR-273572 |
| SYK | phosphorylation → up-regulates activity | SYK | SIGNOR-246605 |
| SYK | phosphorylation → up-regulates activity | EZR | SIGNOR-279129 |
| SYK | phosphorylation → up-regulates activity | MAP4K1 | SIGNOR-246567 |
| SYK | phosphorylation → up-regulates activity | GCSAM | SIGNOR-273573 |
| SYK | phosphorylation → up-regulates activity | DUSP3 | SIGNOR-275999 |
| SYK | phosphorylation → up-regulates | SHC1 | SIGNOR-59635 |
| SYK | phosphorylation → up-regulates activity | LAT2 | SIGNOR-273575 |
| SYK | phosphorylation → up-regulates | IKZF1 | SIGNOR-199100 |
| SYK | phosphorylation down-regulates | SNCA | SIGNOR-113069 |
| SYK | phosphorylation → up-regulates activity | PLCG1 | SIGNOR-246572 |
| SYK | phosphorylation → up-regulates activity | TUBA4A | SIGNOR-246626 |
| SYK | phosphorylation → up-regulates activity | FCGR2C | SIGNOR-262674 |
| SYK | phosphorylation → up-regulates activity | FCGR2C | SIGNOR-262675 |
| SYK | phosphorylation → up-regulates activity | GCSAM | SIGNOR-273571 |
| SYK | phosphorylation → up-regulates | VAV1 | SIGNOR-107046 |
| SYK | phosphorylation → down-regulates activity | CDC25C | SIGNOR-278328 |
| SYK | phosphorylation → up-regulates | SHC1 | SIGNOR-59639 |
| SYK | phosphorylation → up-regulates | SLC4A1 | SIGNOR-80788 |
| SYK | phosphorylation → up-regulates activity | FLT3 | SIGNOR-278430 |
| SYK | phosphorylation → up-regulates activity | GCSAM | SIGNOR-273574 |
| SYK | phosphorylation → up-regulates activity | SYK | SIGNOR-246601 |
| SYK | phosphorylation → up-regulates activity | LAX1 | SIGNOR-273535 |
| SYK | phosphorylation → up-regulates | BLNK | SIGNOR-96048 |
| SYK | phosphorylation down-regulates | SNCA | SIGNOR-113065 |
| SYK | phosphorylation → up-regulates activity | SH3BP2 | SIGNOR-246596 |
| SYK | phosphorylation → up-regulates activity | SH3BP2 | SIGNOR-246592 |
| SYK | phosphorylation → up-regulates activity | LAX1 | SIGNOR-273533 |
| SYK | phosphorylation → up-regulates | SLC4A1 | SIGNOR-80792 |
| SYK | phosphorylation → up-regulates activity | CGAS | SIGNOR-277845 |
| SYK | phosphorylation → up-regulates activity | SYK | SIGNOR-246609 |
| SYK | phosphorylation → up-regulates activity | LAT2 | SIGNOR-273576 |
| SYK | phosphorylation → up-regulates | SHC1 | SIGNOR-59643 |