| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | SYK | Ser295 | GIISRIKsYSFPKPG | phosphorylation down-regulates | 22585575 | SIGNOR-197528 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | phosphorylation up-regulates → | SYK PSer295 | phosphorylation down-regulates ⊣ | SYK | 22585575 | SIGNOR-197528 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CHEK1 | phosphorylation down-regulates | SYK | SIGNOR-197528 |
