| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCE | KIR3DL1 | Ser415 | QRKITRPsQRPKTPP | phosphorylation down-regulates | 17911614 | SIGNOR-158129 |
| PRKCA | KIR3DL1 | Ser415 | QRKITRPsQRPKTPP | phosphorylation down-regulates activity | 17911614 | SIGNOR-276080 |
| PRKCG | KIR3DL1 | Ser415 | QRKITRPsQRPKTPP | phosphorylation down-regulates | 17911614 | SIGNOR-158133 |
| PRKCB | KIR3DL1 | Ser415 | QRKITRPsQRPKTPP | phosphorylation down-regulates activity | 17911614 | SIGNOR-276079 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCE | phosphorylation up-regulates → | KIR3DL1 PSer415 | phosphorylation down-regulates ⊣ | KIR3DL1 | 17911614 | SIGNOR-158129 |
| PRKCA | phosphorylation up-regulates → | KIR3DL1 PSer415 | phosphorylation down-regulates ⊣ | KIR3DL1 | 17911614 | SIGNOR-276080 |
| PRKCG | phosphorylation up-regulates → | KIR3DL1 PSer415 | phosphorylation down-regulates ⊣ | KIR3DL1 | 17911614 | SIGNOR-158133 |
| PRKCB | phosphorylation up-regulates → | KIR3DL1 PSer415 | phosphorylation down-regulates ⊣ | KIR3DL1 | 17911614 | SIGNOR-276079 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCE | phosphorylation down-regulates | KIR3DL1 | SIGNOR-158129 |
| PRKCA | phosphorylation → down-regulates activity | KIR3DL1 | SIGNOR-276080 |
| PRKCG | phosphorylation down-regulates | KIR3DL1 | SIGNOR-158133 |
| PRKCB | phosphorylation → down-regulates activity | KIR3DL1 | SIGNOR-276079 |
