Entity Details

Name MAP2K4_Tyr185
ID P45983
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAP2K4MAPK8Tyr185TSFMMTPyVVTRYYRphosphorylation
up-regulates activity		9724739SIGNOR-249654
MAP2K7MAPK8Tyr185TSFMMTPyVVTRYYRphosphorylation
up-regulates		9312068SIGNOR-51203
MAP2K4MAPK8Tyr185TSFMMTPyVVTRYYRphosphorylation
up-regulates activity		11062067SIGNOR-251419
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAP2K4phosphorylation
up-regulates
→
MAPK8
PTyr185		phosphorylation
up-regulates
→		MAPK89724739SIGNOR-249654
MAP2K7phosphorylation
up-regulates
→
MAPK8
PTyr185		phosphorylation
up-regulates
→		MAPK89312068SIGNOR-51203
MAP2K4phosphorylation
up-regulates
→
MAPK8
PTyr185		phosphorylation
up-regulates
→		MAPK811062067SIGNOR-251419
Regulator Mechanism/Effect Target SIGNOR-ID
MAP2K4phosphorylation
→
up-regulates activity 		MAPK8SIGNOR-249654
MAP2K7phosphorylation
→
up-regulates 		MAPK8SIGNOR-51203
MAP2K4phosphorylation
→
up-regulates activity 		MAPK8SIGNOR-251419