Entity Details

Name PHKA1
ID P46020
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKACBPHKA1–phosphorylation
down-regulates activity		10487978SIGNOR-267413
PKAPHKA1–phosphorylation
down-regulates activity		10487978SIGNOR-267409
PHKA1PHKA1Ser985
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SNVSPAIsIHEIGAVphosphorylation
up-regulates activity		10487978SIGNOR-250282
PHKA1PHKA1Ser1007TGIMQLKsEIKQVEFphosphorylation
up-regulates activity		10487978SIGNOR-250280
PRKACGPHKA1–phosphorylation
down-regulates activity		10487978SIGNOR-267415
PHKA1PHKA1Ser972
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KEFGVERsVRPTDSNphosphorylation
up-regulates activity		10487978SIGNOR-250281
PRKACAPHKA1Ser1018
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QVEFRRLsISAESQSphosphorylation
up-regulates activity		10487978SIGNOR-250026
PRKACAPHKA1–phosphorylation
up-regulates activity		10487978SIGNOR-267411
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PHKA1phosphorylation
up-regulates
→
PHKA1
PSer985		phosphorylation
up-regulates
→		PHKA110487978SIGNOR-250282
PHKA1phosphorylation
up-regulates
→
PHKA1
PSer1007		phosphorylation
up-regulates
→		PHKA110487978SIGNOR-250280
PHKA1phosphorylation
up-regulates
→
PHKA1
PSer972		phosphorylation
up-regulates
→		PHKA110487978SIGNOR-250281
PRKACAphosphorylation
up-regulates
→
PHKA1
PSer1018		phosphorylation
up-regulates
→		PHKA110487978SIGNOR-250026
Regulator Mechanism/Effect Target SIGNOR-ID
PRKACBphosphorylation
→
down-regulates activity 		PHKA1SIGNOR-267413
PKAphosphorylation
→
down-regulates activity 		PHKA1SIGNOR-267409
PHKA1phosphorylation
→
up-regulates activity 		PHKA1SIGNOR-250282
PHKA1phosphorylation
→
up-regulates activity 		PHKA1SIGNOR-250280
PRKACGphosphorylation
→
down-regulates activity 		PHKA1SIGNOR-267415
PHKA1phosphorylation
→
up-regulates activity 		PHKA1SIGNOR-250281
PRKACAphosphorylation
→
up-regulates activity 		PHKA1SIGNOR-250026
PRKACAphosphorylation
→
up-regulates activity 		PHKA1SIGNOR-267411