| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | RANGAP1 | Ser442 | STFLAFPsPEKLLRL | phosphorylation up-regulates | 15037602 | SIGNOR-123520 |
| CyclinB/CDK1 | RANGAP1 | Ser428 | EPAPVLSsPPPADVS | phosphorylation up-regulates | 15037602 | SIGNOR-216781 |
| CyclinB/CDK1 | RANGAP1 | Ser442 | STFLAFPsPEKLLRL | phosphorylation up-regulates | 15037602 | SIGNOR-216785 |
| CyclinB/CDK1 | RANGAP1 | Thr409 | GQGEKSAtPSRKILD | phosphorylation up-regulates | 15037602 | SIGNOR-216789 |
| CDK1 | RANGAP1 | Thr409 | GQGEKSAtPSRKILD | phosphorylation up-regulates | 15037602 | SIGNOR-123524 |
| CDK1 | RANGAP1 | Ser428 | EPAPVLSsPPPADVS | phosphorylation up-regulates | 15037602 | SIGNOR-123516 |
| CSNK2A1 | RANGAP1 | Ser358 | AKVLASLsDDEDEEE | phosphorylation up-regulates | 16428860 | SIGNOR-143948 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | phosphorylation up-regulates → | RANGAP1 PSer442 | phosphorylation up-regulates → | RANGAP1 | 15037602 | SIGNOR-123520 |
| CyclinB/CDK1 | phosphorylation up-regulates → | RANGAP1 PSer428 | phosphorylation up-regulates → | RANGAP1 | 15037602 | SIGNOR-216781 |
| CyclinB/CDK1 | phosphorylation up-regulates → | RANGAP1 PSer442 | phosphorylation up-regulates → | RANGAP1 | 15037602 | SIGNOR-216785 |
| CyclinB/CDK1 | phosphorylation up-regulates → | RANGAP1 PThr409 | phosphorylation up-regulates → | RANGAP1 | 15037602 | SIGNOR-216789 |
| CDK1 | phosphorylation up-regulates → | RANGAP1 PThr409 | phosphorylation up-regulates → | RANGAP1 | 15037602 | SIGNOR-123524 |
| CDK1 | phosphorylation up-regulates → | RANGAP1 PSer428 | phosphorylation up-regulates → | RANGAP1 | 15037602 | SIGNOR-123516 |
| CSNK2A1 | phosphorylation up-regulates → | RANGAP1 PSer358 | phosphorylation up-regulates → | RANGAP1 | 16428860 | SIGNOR-143948 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK1 | phosphorylation → up-regulates | RANGAP1 | SIGNOR-123520 |
| CyclinB/CDK1 | phosphorylation → up-regulates | RANGAP1 | SIGNOR-216781 |
| CyclinB/CDK1 | phosphorylation → up-regulates | RANGAP1 | SIGNOR-216785 |
| CyclinB/CDK1 | phosphorylation → up-regulates | RANGAP1 | SIGNOR-216789 |
| CDK1 | phosphorylation → up-regulates | RANGAP1 | SIGNOR-123524 |
| CDK1 | phosphorylation → up-regulates | RANGAP1 | SIGNOR-123516 |
| CSNK2A1 | phosphorylation → up-regulates | RANGAP1 | SIGNOR-143948 |
