Entity Details

Name NOTCH1_Ser2439
ID P46531
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PLK1NOTCH1Ser2439SFLSGEPsQADVQPLphosphorylation
down-regulates quantity by destabilization		31597699SIGNOR-277490
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PLK1phosphorylation
up-regulates
→
NOTCH1
PSer2439		phosphorylation
down-regulates
⊣		NOTCH131597699SIGNOR-277490
Regulator Mechanism/Effect Target SIGNOR-ID
PLK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		NOTCH1SIGNOR-277490