| Name | MAP2K3 |
| ID | P46734 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 64-325 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP3K3 | MAP2K3 | Ser218 | ISGYLVDsVAKTMDA | phosphorylation up-regulates activity | 9162092 | SIGNOR-48625 |
| TAOK1 | MAP2K3 | Ser218 | ISGYLVDsVAKTMDA | phosphorylation up-regulates activity | 9786855 | SIGNOR-60818 |
| MAP3K11 | MAP2K3 | – | phosphorylation up-regulates activity | 9003778 | SIGNOR-45788 | |
| TAOK2 | MAP2K3 | Ser218 | ISGYLVDsVAKTMDA | phosphorylation up-regulates activity | 11279118 | SIGNOR-106462 |
| LRRK2 | MAP2K3 | – | phosphorylation up-regulates activity | 20067578 | SIGNOR-279057 | |
| MAP3K5 | MAP2K3 | Ser218 | ISGYLVDsVAKTMDA | phosphorylation up-regulates activity | 19920149 | SIGNOR-161763 |
| MAP3K7 | MAP2K3 | – | phosphorylation up-regulates activity | 21902831 | SIGNOR-236093 | |
| MAP3K7 | MAP2K3 | – | phosphorylation up-regulates activity | 17299140 | SIGNOR-42402 | |
| MAP3K5 | MAP2K3 | – | phosphorylation up-regulates activity | 8974401 | SIGNOR-226672 | |
| MAP3K4 | MAP2K3 | – | phosphorylation up-regulates activity | 9305639 | SIGNOR-50891 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP3K3 | phosphorylation up-regulates → | MAP2K3 PSer218 | phosphorylation up-regulates → | MAP2K3 | 9162092 | SIGNOR-48625 |
| TAOK1 | phosphorylation up-regulates → | MAP2K3 PSer218 | phosphorylation up-regulates → | MAP2K3 | 9786855 | SIGNOR-60818 |
| TAOK2 | phosphorylation up-regulates → | MAP2K3 PSer218 | phosphorylation up-regulates → | MAP2K3 | 11279118 | SIGNOR-106462 |
| MAP3K5 | phosphorylation up-regulates → | MAP2K3 PSer218 | phosphorylation up-regulates → | MAP2K3 | 19920149 | SIGNOR-161763 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAP3K3 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-48625 |
| TAOK1 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-60818 |
| MAP3K11 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-45788 |
| TAOK2 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-106462 |
| LRRK2 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-279057 |
| MAP3K5 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-161763 |
| MAP3K7 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-236093 |
| MAP3K7 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-42402 |
| MAP3K5 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-226672 |
| MAP3K4 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-50891 |