| Name | YAP1 |
| ID | P46937 |
| Role | substrate |
| Enzymatic Domains |
WW 1 171-204 PROSITE-ProRule
WW 2 230-263 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP3K7 | YAP1 | Ser127 | PQHVRAHsSPASLQL | phosphorylation down-regulates activity | 30385786 | SIGNOR-278956 |
| CSNK1E | YAP1 | Ser403 | ESTDSGLsMSSYSVP | phosphorylation down-regulates | 24715453 | SIGNOR-230733 |
| CSNK1E | YAP1 | Ser403 | ESTDSGLsMSSYSVP | phosphorylation down-regulates | 23431053 | SIGNOR-201170 |
| JNK | YAP1 | Ser367 | GTQNPVSsPGMSQEL | phosphorylation up-regulates activity | 21364637 | SIGNOR-277644 |
| CDK1 | YAP1 | Ser138 | SLQLGAVsPGTLTPT | phosphorylation up-regulates activity | 26933062 | SIGNOR-276589 |
| CDK1 | YAP1 | Ser289 | PPPLAPQsPQGGVMG | phosphorylation up-regulates activity | 24101154 | SIGNOR-279362 |
| NEK2 | YAP1 | Thr143 | AVSPGTLtPTGVVSG | phosphorylation up-regulates quantity by stabilization | 35705994 | SIGNOR-276586 |
| CSNK1D | YAP1 | Ser400 | SRDESTDsGLSMSSY | phosphorylation down-regulates | 23431053 | SIGNOR-201143 |
| JNK | YAP1 | Thr119 | AGTAGALtPQHVRAH | phosphorylation up-regulates activity | 21364637 | SIGNOR-277641 |
| STK25 | YAP1 | – | phosphorylation up-regulates activity | 30948712 | SIGNOR-278993 | |
| CDK8 | YAP1 | Ser367 | GTQNPVSsPGMSQEL | phosphorylation up-regulates activity | 29967145 | SIGNOR-277651 |
| LATS2 | YAP1 | Ser127 | PQHVRAHsSPASLQL | phosphorylation down-regulates | 22863277 | SIGNOR-198514 |
| STK38 | YAP1 | Ser127 | PQHVRAHsSPASLQL | phosphorylation down-regulates activity | 25601544 | SIGNOR-259855 |
| CSNK1E | YAP1 | Ser400 | SRDESTDsGLSMSSY | phosphorylation down-regulates | 23431053 | SIGNOR-201165 |
| STK26 | YAP1 | Thr83 | KTANVPQtVPMRLRK | phosphorylation down-regulates activity | 32271880 | SIGNOR-278994 |
| STK38 | YAP1 | Ser109 | KSHSRQAsTDAGTAG | phosphorylation down-regulates activity | 25601544 | SIGNOR-259856 |
| mTORC2 | YAP1 | Ser436 | INQSTLPsQQNRFPD | phosphorylation up-regulates activity | 34343821 | SIGNOR-277569 |
| IKBKE | YAP1 | Ser419 | TPDDFLNsVDEMDTG | phosphorylation down-regulates quantity by destabilization | 28481329 | SIGNOR-277355 |
| JNK | YAP1 | Ser138 | SLQLGAVsPGTLTPT | phosphorylation up-regulates activity | 21364637 | SIGNOR-277642 |
| CSNK1D | YAP1 | Ser400 | SRDESTDsGLSMSSY | phosphorylation down-regulates | 24715453 | SIGNOR-230738 |
| YES1 | YAP1 | Tyr391 | PFLNSGTyHSRDEST | phosphorylation up-regulates activity | 35041461 | SIGNOR-277652 |
| ABL1 | YAP1 | Tyr407 | SGLSMSSySVPRTPD | phosphorylation up-regulates | 18280240 | SIGNOR-160860 |
| FRK | YAP1 | Tyr391 | PFLNSGTyHSRDEST | phosphorylation down-regulates quantity by destabilization | 35723276 | SIGNOR-275455 |
| CDK1 | YAP1 | Ser367 | GTQNPVSsPGMSQEL | phosphorylation up-regulates activity | 26933062 | SIGNOR-276587 |
| CyclinB/CDK1 | YAP1 | Thr143 | AVSPGTLtPTGVVSG | phosphorylation up-regulates activity | 26933062 | SIGNOR-276591 |
| PPM1A | YAP1 | Ser127 | PQHVRAHsSPASLQL | dephosphorylation up-regulates activity | 33630828 | SIGNOR-276984 |
| AMPK | YAP1 | Ser94 | RLRKLPDsFFKPPEP | phosphorylation down-regulates activity | 25751140 | SIGNOR-277638 |
| FRK | YAP1 | Tyr444 | QQNRFPDyLEAIPGT | phosphorylation down-regulates quantity by destabilization | 35723276 | SIGNOR-275457 |
| NLK | YAP1 | Ser128 | QHVRAHSsPASLQLG | phosphorylation up-regulates activity | 27979971 | SIGNOR-273909 |
| CDK1 | YAP1 | Ser367 | GTQNPVSsPGMSQEL | phosphorylation up-regulates activity | 24101154 | SIGNOR-279363 |
| LATS1 | YAP1 | Ser397 | TYHSRDEsTDSGLSM | phosphorylation down-regulates quantity by destabilization | 20048001 | SIGNOR-218034 |
| CDK1 | YAP1 | Thr143 | AVSPGTLtPTGVVSG | phosphorylation up-regulates activity | 26933062 | SIGNOR-276588 |
| ULK1 | YAP1 | Ser227 | VQQNMMNsASGPLPD | phosphorylation up-regulates quantity by stabilization | 34345207 | SIGNOR-277570 |
| AKT | YAP1 | Ser127 | PQHVRAHsSPASLQL | phosphorylation down-regulates | 12535517 | SIGNOR-97485 |
| LATS2 | YAP1 | Ser397 | TYHSRDEsTDSGLSM | phosphorylation down-regulates quantity by destabilization | 20048001 | SIGNOR-218038 |
| LATS1/2 | YAP1 | Ser397 | TYHSRDEsTDSGLSM | phosphorylation down-regulates quantity by destabilization | 20048001 | SIGNOR-277636 |
| CDK8 | YAP1 | Ser289 | PPPLAPQsPQGGVMG | phosphorylation up-regulates activity | 29967145 | SIGNOR-277650 |
| PTK2 | YAP1 | – | phosphorylation up-regulates activity | 33498611 | SIGNOR-280099 | |
| CDK1 | YAP1 | Thr119 | AGTAGALtPQHVRAH | phosphorylation up-regulates activity | 24101154 | SIGNOR-279361 |
| AKT1 | YAP1 | Ser127 | PQHVRAHsSPASLQL | phosphorylation down-regulates | 12535517 | SIGNOR-252593 |
| JNK | YAP1 | Thr154 | VVSGPAAtPTAQHLR | phosphorylation up-regulates activity | 21364637 | SIGNOR-277643 |
| PPP1CA | YAP1 | Ser127 | PQHVRAHsSPASLQL | dephosphorylation up-regulates activity | 21909427 | SIGNOR-276999 |
| FRK | YAP1 | Tyr407 | SGLSMSSySVPRTPD | phosphorylation down-regulates quantity by destabilization | 35723276 | SIGNOR-275456 |
| CSNK1E | YAP1 | Ser400 | SRDESTDsGLSMSSY | phosphorylation down-regulates | 24715453 | SIGNOR-230728 |
| CDK8 | YAP1 | Ser128 | QHVRAHSsPASLQLG | phosphorylation up-regulates activity | 29967145 | SIGNOR-277649 |
| CSNK1D | YAP1 | Ser403 | ESTDSGLsMSSYSVP | phosphorylation down-regulates | 23431053 | SIGNOR-201154 |
| PRKCZ | YAP1 | Thr110 | SHSRQAStDAGTAGA | phosphorylation down-regulates quantity by destabilization | 25660024 | SIGNOR-276877 |
| CyclinB/CDK1 | YAP1 | Ser138 | SLQLGAVsPGTLTPT | phosphorylation up-regulates activity | 26933062 | SIGNOR-276592 |
| LATS1 | YAP1 | Ser127 | PQHVRAHsSPASLQL | phosphorylation down-regulates | 22658639 | SIGNOR-197647 |
| PRKCZ | YAP1 | Ser109 | KSHSRQAsTDAGTAG | phosphorylation down-regulates quantity by destabilization | 25660024 | SIGNOR-276876 |
| JNK | YAP1 | Ser400 | SRDESTDsGLSMSSY | phosphorylation up-regulates activity | 21364637 | SIGNOR-277645 |
| LATS1/2 | YAP1 | Ser127 | PQHVRAHsSPASLQL | phosphorylation down-regulates activity | 22658639 | SIGNOR-256188 |
| LATS2 | YAP1 | Ser127 | PQHVRAHsSPASLQL | phosphorylation down-regulates | 22658639 | SIGNOR-197655 |
| CyclinB/CDK1 | YAP1 | Ser367 | GTQNPVSsPGMSQEL | phosphorylation up-regulates activity | 26933062 | SIGNOR-276590 |
| CSNK1D | YAP1 | Ser403 | ESTDSGLsMSSYSVP | phosphorylation down-regulates | 24715453 | SIGNOR-230743 |
| YES1 | YAP1 | Tyr407 | SGLSMSSySVPRTPD | phosphorylation up-regulates activity | 23245941 | SIGNOR-278248 |
| CDK8 | YAP1 | Thr119 | AGTAGALtPQHVRAH | phosphorylation up-regulates activity | 29967145 | SIGNOR-277648 |
| YES1 | YAP1 | Tyr407 | SGLSMSSySVPRTPD | phosphorylation up-regulates activity | 35041461 | SIGNOR-277653 |
| STK11 | YAP1 | – | phosphorylation down-regulates activity | 23027127 | SIGNOR-280139 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP3K7 | phosphorylation up-regulates → | YAP1 PSer127 | phosphorylation down-regulates ⊣ | YAP1 | 30385786 | SIGNOR-278956 |
| CSNK1E | phosphorylation up-regulates → | YAP1 PSer403 | phosphorylation down-regulates ⊣ | YAP1 | 24715453 | SIGNOR-230733 |
| CSNK1E | phosphorylation up-regulates → | YAP1 PSer403 | phosphorylation down-regulates ⊣ | YAP1 | 23431053 | SIGNOR-201170 |
| JNK | phosphorylation up-regulates → | YAP1 PSer367 | phosphorylation up-regulates → | YAP1 | 21364637 | SIGNOR-277644 |
| CDK1 | phosphorylation up-regulates → | YAP1 PSer138 | phosphorylation up-regulates → | YAP1 | 26933062 | SIGNOR-276589 |
| CDK1 | phosphorylation up-regulates → | YAP1 PSer289 | phosphorylation up-regulates → | YAP1 | 24101154 | SIGNOR-279362 |
| NEK2 | phosphorylation up-regulates → | YAP1 PThr143 | phosphorylation up-regulates → | YAP1 | 35705994 | SIGNOR-276586 |
| CSNK1D | phosphorylation up-regulates → | YAP1 PSer400 | phosphorylation down-regulates ⊣ | YAP1 | 23431053 | SIGNOR-201143 |
| JNK | phosphorylation up-regulates → | YAP1 PThr119 | phosphorylation up-regulates → | YAP1 | 21364637 | SIGNOR-277641 |
| CDK8 | phosphorylation up-regulates → | YAP1 PSer367 | phosphorylation up-regulates → | YAP1 | 29967145 | SIGNOR-277651 |
| LATS2 | phosphorylation up-regulates → | YAP1 PSer127 | phosphorylation down-regulates ⊣ | YAP1 | 22863277 | SIGNOR-198514 |
| STK38 | phosphorylation up-regulates → | YAP1 PSer127 | phosphorylation down-regulates ⊣ | YAP1 | 25601544 | SIGNOR-259855 |
| CSNK1E | phosphorylation up-regulates → | YAP1 PSer400 | phosphorylation down-regulates ⊣ | YAP1 | 23431053 | SIGNOR-201165 |
| STK26 | phosphorylation up-regulates → | YAP1 PThr83 | phosphorylation down-regulates ⊣ | YAP1 | 32271880 | SIGNOR-278994 |
| STK38 | phosphorylation up-regulates → | YAP1 PSer109 | phosphorylation down-regulates ⊣ | YAP1 | 25601544 | SIGNOR-259856 |
| mTORC2 | phosphorylation up-regulates → | YAP1 PSer436 | phosphorylation up-regulates → | YAP1 | 34343821 | SIGNOR-277569 |
| IKBKE | phosphorylation up-regulates → | YAP1 PSer419 | phosphorylation down-regulates ⊣ | YAP1 | 28481329 | SIGNOR-277355 |
| JNK | phosphorylation up-regulates → | YAP1 PSer138 | phosphorylation up-regulates → | YAP1 | 21364637 | SIGNOR-277642 |
| CSNK1D | phosphorylation up-regulates → | YAP1 PSer400 | phosphorylation down-regulates ⊣ | YAP1 | 24715453 | SIGNOR-230738 |
| YES1 | phosphorylation up-regulates → | YAP1 PTyr391 | phosphorylation up-regulates → | YAP1 | 35041461 | SIGNOR-277652 |
| ABL1 | phosphorylation up-regulates → | YAP1 PTyr407 | phosphorylation up-regulates → | YAP1 | 18280240 | SIGNOR-160860 |
| FRK | phosphorylation up-regulates → | YAP1 PTyr391 | phosphorylation down-regulates ⊣ | YAP1 | 35723276 | SIGNOR-275455 |
| CDK1 | phosphorylation up-regulates → | YAP1 PSer367 | phosphorylation up-regulates → | YAP1 | 26933062 | SIGNOR-276587 |
| CyclinB/CDK1 | phosphorylation up-regulates → | YAP1 PThr143 | phosphorylation up-regulates → | YAP1 | 26933062 | SIGNOR-276591 |
| PPM1A | dephosphorylation down-regulates ⊣ | YAP1 PSer127 | dephosphorylation down-regulates ⊣ | YAP1 | 33630828 | SIGNOR-276984 |
| AMPK | phosphorylation up-regulates → | YAP1 PSer94 | phosphorylation down-regulates ⊣ | YAP1 | 25751140 | SIGNOR-277638 |
| FRK | phosphorylation up-regulates → | YAP1 PTyr444 | phosphorylation down-regulates ⊣ | YAP1 | 35723276 | SIGNOR-275457 |
| NLK | phosphorylation up-regulates → | YAP1 PSer128 | phosphorylation up-regulates → | YAP1 | 27979971 | SIGNOR-273909 |
| CDK1 | phosphorylation up-regulates → | YAP1 PSer367 | phosphorylation up-regulates → | YAP1 | 24101154 | SIGNOR-279363 |
| LATS1 | phosphorylation up-regulates → | YAP1 PSer397 | phosphorylation down-regulates ⊣ | YAP1 | 20048001 | SIGNOR-218034 |
| CDK1 | phosphorylation up-regulates → | YAP1 PThr143 | phosphorylation up-regulates → | YAP1 | 26933062 | SIGNOR-276588 |
| ULK1 | phosphorylation up-regulates → | YAP1 PSer227 | phosphorylation up-regulates → | YAP1 | 34345207 | SIGNOR-277570 |
| AKT | phosphorylation up-regulates → | YAP1 PSer127 | phosphorylation down-regulates ⊣ | YAP1 | 12535517 | SIGNOR-97485 |
| LATS2 | phosphorylation up-regulates → | YAP1 PSer397 | phosphorylation down-regulates ⊣ | YAP1 | 20048001 | SIGNOR-218038 |
| LATS1/2 | phosphorylation up-regulates → | YAP1 PSer397 | phosphorylation down-regulates ⊣ | YAP1 | 20048001 | SIGNOR-277636 |
| CDK8 | phosphorylation up-regulates → | YAP1 PSer289 | phosphorylation up-regulates → | YAP1 | 29967145 | SIGNOR-277650 |
| CDK1 | phosphorylation up-regulates → | YAP1 PThr119 | phosphorylation up-regulates → | YAP1 | 24101154 | SIGNOR-279361 |
| AKT1 | phosphorylation up-regulates → | YAP1 PSer127 | phosphorylation down-regulates ⊣ | YAP1 | 12535517 | SIGNOR-252593 |
| JNK | phosphorylation up-regulates → | YAP1 PThr154 | phosphorylation up-regulates → | YAP1 | 21364637 | SIGNOR-277643 |
| PPP1CA | dephosphorylation down-regulates ⊣ | YAP1 PSer127 | dephosphorylation down-regulates ⊣ | YAP1 | 21909427 | SIGNOR-276999 |
| FRK | phosphorylation up-regulates → | YAP1 PTyr407 | phosphorylation down-regulates ⊣ | YAP1 | 35723276 | SIGNOR-275456 |
| CSNK1E | phosphorylation up-regulates → | YAP1 PSer400 | phosphorylation down-regulates ⊣ | YAP1 | 24715453 | SIGNOR-230728 |
| CDK8 | phosphorylation up-regulates → | YAP1 PSer128 | phosphorylation up-regulates → | YAP1 | 29967145 | SIGNOR-277649 |
| CSNK1D | phosphorylation up-regulates → | YAP1 PSer403 | phosphorylation down-regulates ⊣ | YAP1 | 23431053 | SIGNOR-201154 |
| PRKCZ | phosphorylation up-regulates → | YAP1 PThr110 | phosphorylation down-regulates ⊣ | YAP1 | 25660024 | SIGNOR-276877 |
| CyclinB/CDK1 | phosphorylation up-regulates → | YAP1 PSer138 | phosphorylation up-regulates → | YAP1 | 26933062 | SIGNOR-276592 |
| LATS1 | phosphorylation up-regulates → | YAP1 PSer127 | phosphorylation down-regulates ⊣ | YAP1 | 22658639 | SIGNOR-197647 |
| PRKCZ | phosphorylation up-regulates → | YAP1 PSer109 | phosphorylation down-regulates ⊣ | YAP1 | 25660024 | SIGNOR-276876 |
| JNK | phosphorylation up-regulates → | YAP1 PSer400 | phosphorylation up-regulates → | YAP1 | 21364637 | SIGNOR-277645 |
| LATS1/2 | phosphorylation up-regulates → | YAP1 PSer127 | phosphorylation down-regulates ⊣ | YAP1 | 22658639 | SIGNOR-256188 |
| LATS2 | phosphorylation up-regulates → | YAP1 PSer127 | phosphorylation down-regulates ⊣ | YAP1 | 22658639 | SIGNOR-197655 |
| CyclinB/CDK1 | phosphorylation up-regulates → | YAP1 PSer367 | phosphorylation up-regulates → | YAP1 | 26933062 | SIGNOR-276590 |
| CSNK1D | phosphorylation up-regulates → | YAP1 PSer403 | phosphorylation down-regulates ⊣ | YAP1 | 24715453 | SIGNOR-230743 |
| YES1 | phosphorylation up-regulates → | YAP1 PTyr407 | phosphorylation up-regulates → | YAP1 | 23245941 | SIGNOR-278248 |
| CDK8 | phosphorylation up-regulates → | YAP1 PThr119 | phosphorylation up-regulates → | YAP1 | 29967145 | SIGNOR-277648 |
| YES1 | phosphorylation up-regulates → | YAP1 PTyr407 | phosphorylation up-regulates → | YAP1 | 35041461 | SIGNOR-277653 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAP3K7 | phosphorylation → down-regulates activity | YAP1 | SIGNOR-278956 |
| CSNK1E | phosphorylation down-regulates | YAP1 | SIGNOR-230733 |
| CSNK1E | phosphorylation down-regulates | YAP1 | SIGNOR-201170 |
| JNK | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277644 |
| CDK1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-276589 |
| CDK1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-279362 |
| NEK2 | phosphorylation → up-regulates quantity by stabilization | YAP1 | SIGNOR-276586 |
| CSNK1D | phosphorylation down-regulates | YAP1 | SIGNOR-201143 |
| JNK | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277641 |
| STK25 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-278993 |
| CDK8 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277651 |
| LATS2 | phosphorylation down-regulates | YAP1 | SIGNOR-198514 |
| STK38 | phosphorylation → down-regulates activity | YAP1 | SIGNOR-259855 |
| CSNK1E | phosphorylation down-regulates | YAP1 | SIGNOR-201165 |
| STK26 | phosphorylation → down-regulates activity | YAP1 | SIGNOR-278994 |
| STK38 | phosphorylation → down-regulates activity | YAP1 | SIGNOR-259856 |
| mTORC2 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277569 |
| IKBKE | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-277355 |
| JNK | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277642 |
| CSNK1D | phosphorylation down-regulates | YAP1 | SIGNOR-230738 |
| YES1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277652 |
| ABL1 | phosphorylation → up-regulates | YAP1 | SIGNOR-160860 |
| FRK | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-275455 |
| CDK1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-276587 |
| CyclinB/CDK1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-276591 |
| PPM1A | dephosphorylation → up-regulates activity | YAP1 | SIGNOR-276984 |
| AMPK | phosphorylation → down-regulates activity | YAP1 | SIGNOR-277638 |
| FRK | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-275457 |
| NLK | phosphorylation → up-regulates activity | YAP1 | SIGNOR-273909 |
| CDK1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-279363 |
| LATS1 | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-218034 |
| CDK1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-276588 |
| ULK1 | phosphorylation → up-regulates quantity by stabilization | YAP1 | SIGNOR-277570 |
| AKT | phosphorylation down-regulates | YAP1 | SIGNOR-97485 |
| LATS2 | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-218038 |
| LATS1/2 | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-277636 |
| CDK8 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277650 |
| PTK2 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-280099 |
| CDK1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-279361 |
| AKT1 | phosphorylation down-regulates | YAP1 | SIGNOR-252593 |
| JNK | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277643 |
| PPP1CA | dephosphorylation → up-regulates activity | YAP1 | SIGNOR-276999 |
| FRK | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-275456 |
| CSNK1E | phosphorylation down-regulates | YAP1 | SIGNOR-230728 |
| CDK8 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277649 |
| CSNK1D | phosphorylation down-regulates | YAP1 | SIGNOR-201154 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-276877 |
| CyclinB/CDK1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-276592 |
| LATS1 | phosphorylation down-regulates | YAP1 | SIGNOR-197647 |
| PRKCZ | phosphorylation down-regulates quantity by destabilization | YAP1 | SIGNOR-276876 |
| JNK | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277645 |
| LATS1/2 | phosphorylation → down-regulates activity | YAP1 | SIGNOR-256188 |
| LATS2 | phosphorylation down-regulates | YAP1 | SIGNOR-197655 |
| CyclinB/CDK1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-276590 |
| CSNK1D | phosphorylation down-regulates | YAP1 | SIGNOR-230743 |
| YES1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-278248 |
| CDK8 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277648 |
| YES1 | phosphorylation → up-regulates activity | YAP1 | SIGNOR-277653 |
| STK11 | phosphorylation → down-regulates activity | YAP1 | SIGNOR-280139 |